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Transepithelial High-Intensity Cross-Linking for the Treatment of Progressive Keratoconus: 2-year Outcomes

التفاصيل البيبلوغرافية
العنوان: Transepithelial High-Intensity Cross-Linking for the Treatment of Progressive Keratoconus: 2-year Outcomes
المؤلفون: Muhammet Bahattin Kır, Kemal Türkyilmaz, Veysi Öner
المصدر: Current Eye Research. 42:28-31
بيانات النشر: Informa UK Limited, 2016.
سنة النشر: 2016
مصطلحات موضوعية: Adult, Male, Keratoconus, Refractive error, medicine.medical_specialty, Visual acuity, Adolescent, Corneal Pachymetry, Ultraviolet Rays, Corneal Stroma, Riboflavin, Visual Acuity, Spherical equivalent, Refraction, Ocular, Young Adult, 03 medical and health sciences, Cellular and Molecular Neuroscience, Benzalkonium chloride, 0302 clinical medicine, Cornea, Ophthalmology, medicine, Humans, Photosensitizing Agents, Slit lamp, business.industry, High intensity, Epithelium, Corneal, Corneal Topography, medicine.disease, eye diseases, Sensory Systems, Surgery, Treatment Outcome, medicine.anatomical_structure, Photochemotherapy, 030221 ophthalmology & optometry, Female, Collagen, medicine.symptom, business, 030217 neurology & neurosurgery, Follow-Up Studies, medicine.drug
الوصف: To report 2-year outcomes of transepithelial high-intensity cross-linking (CXL) procedure in the treatment of patients with progressive keratoconus.Forty-eight eyes of 48 consecutive progressive keratoconus patients who underwent transepithelial accelerated CXL procedure were enrolled in the study. Each patient underwent pre- and postoperative comprehensive ophthalmologic examinations including determination of refractive error as spherical equivalent (SE) and corrected distant visual acuity (CDVA), slit lamp biomicroscopic examination, fundoscopy, and a detailed analysis on a Scheimplug+Placido device (Sirius, CSO, Florence, Italy). The riboflavin solution, which was composed of riboflavin 0.25% with hydroxypropyl methylcellulose (HPMC) and benzalkonium chloride (BAC) (ParaCel, Avedro), was used in the procedure. The cornea was exposed to ultraviolet A light (KXL System, Avedro Inc., Waltham, MS, USA) for 2 minutes and 40 seconds at an irradiance of 45 mW/cmThe mean age of the patients was 25.9 ± 4.0 (ranging from 18 to 33) years. No significant changes were observed in the mean CDVA, SE, and topographic indices at year 1 and year 2 visits compared to preoperative examination. The mean corneal thickness at the thinnest point was significantly higher at year 1 and year 2 visits than at preoperative examination (p1 = 0.014 and p2 = 0.017, respectively). No intra- or postoperative complications or adverse reactions were observed.Transepithelial high-intensity (irradiance of 45 mW/cm
تدمد: 1460-2202
0271-3683
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0562c6928ad4c2ff3956842c1928f9
https://doi.org/10.3109/02713683.2016.1148742
رقم الأكسشن: edsair.doi.dedup.....6e0562c6928ad4c2ff3956842c1928f9
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14602202
02713683