Metal wear-induced pseudotumour following an endoprosthetic knee replacement for Ewing sarcoma
| العنوان: | Metal wear-induced pseudotumour following an endoprosthetic knee replacement for Ewing sarcoma |
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| المؤلفون: | Christopher L. M. H. Gibbons, Marianna Vlychou, Richard Craig, Nicholas A. Athanasou, Catherine L. McCarthy |
| المصدر: | Skeletal Radiology |
| بيانات النشر: | Springer Berlin Heidelberg, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Pathology, Surface Properties, medicine.medical_treatment, Knee replacement, Connective tissue, Case Report, Sarcoma, Ewing, Granuloma, Plasma Cell, Lesion, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Pseudotumour, medicine, Humans, Radiology, Nuclear Medicine and imaging, Knee, Arthroplasty, Replacement, Knee, 030222 orthopedics, business.industry, Femoral Neoplasms, Eosinophil, Acquired immune system, medicine.disease, Magnetic Resonance Imaging, Prosthesis Failure, medicine.anatomical_structure, Radiology Nuclear Medicine and imaging, Metals, 030220 oncology & carcinogenesis, Positron-Emission Tomography, Orthopedic surgery, Endoprosthesis, Female, Sarcoma, Stress, Mechanical, medicine.symptom, Complication, business, Metal wear |
| الوصف: | Pseudotumours are well recognised as a complication of metal-on-metal hip arthroplasties and are thought to develop on the basis of an innate and adaptive immune response to cobalt-chrome (Co-Cr) wear particles. We report a case of a large pseudotumour that developed following a knee endoprosthetic replacement (EPR) undertaken for Ewing sarcoma. The lesion contained necrotic and degenerate connective tissue in which there were numerous scattered metal wear-containing macrophages, eosinophil polymorphs, lymphocytes, plasma cells and aseptic lymphocyte-dominated vascular-associated lesion-like lymphoid aggregates. Metal ion levels were elevated. No evidence of infection or tumour was noted and it was concluded that the lesion was most likely an inflammatory pseudotumour developing on the basis of an innate and adaptive immune response to components of Co-Cr metal wear derived from the knee EPR. |
| اللغة: | English |
| تدمد: | 1432-2161 0364-2348 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0d1da51e1721ff79086c9fd3ccf8da http://europepmc.org/articles/PMC5438826 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6f0d1da51e1721ff79086c9fd3ccf8da |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14322161 03642348 |
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