Prospective clinical trial comparing outcome measures between Furlow and Von Langenbeck palatoplasties for UCLP
| العنوان: | Prospective clinical trial comparing outcome measures between Furlow and Von Langenbeck palatoplasties for UCLP |
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| المؤلفون: | Luis A Garla, M. Brent Seagle, Maria Inês Pegoraro-Krook, Marcos L N Silva, José Carlos Jorge, Patrick J. Antonelli, José S M Neto, Angela Patricia Menezes Cardoso Martinelli, John A. Nackashi, Cristina Bento-Gonçalvez, Joseph Kemker, Mariza Ribeiro Feniman, Josiane F. A. Neves, Jacquelyn E. Moorhead, Telma V Souza, Maria Inês Gândara Graciano, William Wharton, Steve Boggs, Melina Evangelista Whitaker, Jonathan J. Shuster, Ilza Lazarini Marques, Sílvia Helena Alvarez Piazentin-Penna, Hilton Coimbra Borgo, William N. Williams, Jeniffer de Cássia Rillo Dutka, Maria Cecíli Pimentel, Maria C Zimmermann |
| المصدر: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | business.industry, Palate, Fistula, Cleft Lip, Outcome measures, Dentistry, Infant, Plastic Surgery Procedures, medicine.disease, law.invention, Clinical trial, Cleft Palate, Primary outcome, Treatment Outcome, Randomized controlled trial, law, medicine, Humans, Surgery, In patient, Prospective Studies, business, Prospective cohort study, PERCEPÇÃO DA FALA, Nasal air emission |
| الوصف: | The goal of this prospective randomized clinical trial was to compare 2 cohorts of standardized cleft patients with regard to functional speech outcome and the presence or absence of palatal fistulae. The 2 cohorts are randomized to undergo either a conventional von Langenbeck repair with intravelar velarplasty or the double-opposing Z-plasty Furlow procedure. A prospective 2 × 2 × 2 factorial clinical trial was used in which each subject was randomly assigned to 1 of 8 different groups: 1 of 2 different lip repairs (Spina vs. Millard), 1 of 2 different palatal repair (von Langenbeck vs. Furlow), and 1 of 2 different ages at time of palatal surgery (9-12 months vs. 15-18 months). All surgeries were performed by the same 4 surgeons. A cul-de-sac test of hypernasality and a mirror test of nasal air emission were selected as primary outcome measures for velopharyngeal function. Both a surgeon and speech pathologist examined patients for the presence of palatal fistulae. In this study, the Furlow double-opposing Z-palatoplasty resulted in significantly better velopharyngeal function for speech than the von Langenbeck procedure as determined by the perceptual cul-de-sac test of hypernasality. Fistula occurrence was significantly higher for the Furlow procedure than for the von Langenbeck. Fistulas were more likely to occur in patients with wider clefts and when relaxing incisions were not used. |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f39707d90dc42e18d08faa785793420 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....6f39707d90dc42e18d08faa785793420 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |