Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis
| العنوان: | Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis |
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| المؤلفون: | Vijayakumar Poondla, Reddemma Uyyala, Sreeharsha Nagaraja, Venkata Ratnam Kamsala, Lakshmi Bestha, Sridevi Tirumalaraju, Lakshman Kumar Lingamgunta, Venkata Prasad Surtineni, Sreenivasulu Dasari, Janardhan Yadav Egi, Muthukumaran Muthulingam, Anthony Johnson Antony Masilamani, Prabhakar Yellanur Konda, Bindu Prasuna Aloor, Vijayakumar Natesan, Ankanna Sade, Krishna Kumar Jaiswal, Ranjani Ramakrishnan, Sreenath Konanki |
| المصدر: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020) |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Biochemistry, Antioxidants, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, Lipid droplet, Medicine, Multidisciplinary, medicine.diagnostic_test, Glycogen, Biological techniques, Lipids, Fruit and Vegetable Juices, Liver, Biotechnology, medicine.medical_specialty, Science, Saccharomyces cerevisiae, Diet, High-Fat, Microbiology, Article, 03 medical and health sciences, Insulin resistance, Internal medicine, Animals, Obesity, Rats, Wistar, Triglycerides, 030109 nutrition & dietetics, Intestinal permeability, business.industry, Probiotics, Body Weight, Musa, Lipid Metabolism, medicine.disease, Rats, Fatty Liver, Oxidative Stress, 030104 developmental biology, Endocrinology, chemistry, Lipid Peroxidation, Insulin Resistance, Steatosis, Steatohepatitis, business, Lipid profile |
| الوصف: | The high fat diet alters intestinal microbiota due to increased intestinal permeability and susceptibility to microbial antigens leads to metabolic endotoxemia. But probiotic juices reported for various health benefits. In this background we hypothesized that pectinase treated probiotic banana juice has diverse effects on HFD induced obesity and non-alcoholic steatohepatitis. 20 weeks fed HFD successfully induced obesity and its associated complications in experimental rats. The supplementation of probiotic banana juice for 5 months at a dose of 5 mL/kg bw/day resulted significant decrease (p p S. cerevisiae yeast can switch anti-obesity, antidiabetic, antioxidative stress, antioxidant and anti-hepatosteatosis effect. This study results will have significant implications for treatment of NAFLD. |
| تدمد: | 2045-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701ef83b5e6e2fdfc826034d4bca1e81 https://doi.org/10.1038/s41598-020-73670-4 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....701ef83b5e6e2fdfc826034d4bca1e81 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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