Effects of Carnoy's solution on blood vessels of the axillary fossa of rats

التفاصيل البيبلوغرافية
العنوان: Effects of Carnoy's solution on blood vessels of the axillary fossa of rats
المؤلفون: Nikola Saulacic, A. Piattelli, Z. Stajčić, Tateyuki Iizuka, Lj Stojcev Stajcic, Tommaso Lombardi
المصدر: International Journal of Oral and Maxillofacial Surgery, Vol. 38, No 8 (2009) pp. 876-879
سنة النشر: 2007
مصطلحات موضوعية: Male, Pathology, Time Factors, Tunica Intima/drug effects/pathology, 0302 clinical medicine, Ethanol/*pharmacology, Axillary artery, Neurons/drug effects/pathology, Wound Healing/physiology, Schwann Cells/drug effects/pathology, Axons/drug effects/pathology, Axilla/innervation, Fixatives/*pharmacology, 030223 otorhinolaryngology, Hyaline, Fixative, Acetic Acid, Axillary Vein/*drug effects/pathology, Neurons, Chloroform/*pharmacology, Axillary Artery/*drug effects/pathology, Anatomy, ddc:617.6, 3. Good health, Odontogenic, medicine.anatomical_structure, Endothelium, Vascular/drug effects/pathology, cardiovascular system, Female, Chloroform, Oral Surgery, medicine.medical_specialty, Hyalin, Endothelium, Acetic Acid/*pharmacology, Hyalin/drug effects, Carnoy's solution, 03 medical and health sciences, Fixatives, medicine.artery, medicine, Animals, Axillary Vein, Rats, Wistar, Axillary fossa, Vein, Wound Healing, Ethanol, business.industry, Elastic Tissue/drug effects/pathology, Endothelial Cells, 030206 dentistry, Elastic Tissue, Fibrosis, Axons, Rats, Otorhinolaryngology, Axilla, Axillary Artery, Surgery, Endothelium, Vascular, Schwann Cells, business, Tunica Intima, Endothelial Cells/drug effects/pathology
الوصف: Carnoy's solution is applied to reduce the recurrence of odontogenic keratocysts and unicystic ameloblastomas. The deleterious action of this fixative on nerves has been studied but no attention has been paid to its effects on nearby vessels. The aim of this study was to investigate the effects of Carnoy's solution on blood vessels. The rat axillary artery and vein were surgically exposed, soaked with Carnoy's solution and kept in place for 2, 5 or 10 min, depending on the treatment group. The 5-min group was followed for 1, 2 and 3 weeks postoperatively. The vessels in the 2-min and 5-min exposure groups showed histological changes to the vessels, represented by focal loss of the endothelium and hyalinization of the wall. These alterations increased in the 10-min group. The vessels in the 3-week observation period revealed signs of recovery. It is concluded that Carnoy's solution can damage blood vessels but the process is reversible for exposure times less than 5 min.
تدمد: 1399-0020
0901-5027
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709c839629919da7ea15bcca4b4f5337
https://pubmed.ncbi.nlm.nih.gov/19427171
حقوق: RESTRICTED
رقم الأكسشن: edsair.doi.dedup.....709c839629919da7ea15bcca4b4f5337
قاعدة البيانات: OpenAIRE