The effect of dexamethasone on time averaged mean velocity in the middle cerebral artery in very low birth weight infants

التفاصيل البيبلوغرافية
العنوان: The effect of dexamethasone on time averaged mean velocity in the middle cerebral artery in very low birth weight infants
المؤلفون: Jean Bottu, Mary Lou Ryan, Jairaj Govan, T. Myhr, Katherine Fong, Arne Ohlsson
المصدر: European Journal of Pediatrics. 153:363-366
بيانات النشر: Springer Science and Business Media LLC, 1994.
سنة النشر: 1994
مصطلحات موضوعية: Ultrasonography, Doppler, Transcranial, medicine.drug_class, Hemodynamics, Dexamethasone, medicine.artery, Heart rate, medicine, Humans, Prospective Studies, Bronchopulmonary Dysplasia, business.industry, Infant, Newborn, Cerebral Arteries, Infant, Low Birth Weight, medicine.disease, Airway Obstruction, Low birth weight, Blood pressure, Bronchopulmonary dysplasia, Anesthesia, Pediatrics, Perinatology and Child Health, Middle cerebral artery, Corticosteroid, medicine.symptom, business, Blood Flow Velocity, medicine.drug
الوصف: The effect of repeated doses of dexamethasone (0.25 mg/kg/dose every 12 h) on time averaged mean velocity in the middle cerebral artery was assessed in ten ventilated very low birth weight infants requiring treatment with dexamethasone for bronchopulmonary dysplasia or airway obstruction. The infants were studied by colour/duplex Doppler technique prior to the administration of the first and the third dose of dexamethasone, and 10, 30, and 120 min after these doses. Dexamethasone treatment was associated with an improvement in infant lung condition, an increase in mean arterial blood pressure and a decrease in heart rate. The time averaged mean velocity was statistically significantly reduced at 120 min after the first dose. This was not associated with a decrease in PCO2. The observed reduction of 18% from baseline in the time averaged mean velocity is unlikely to be of clinical importance.
تدمد: 1432-1076
0340-6199
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71424a2034ac2e27a0f7256ae841deb7
https://doi.org/10.1007/bf01956420
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....71424a2034ac2e27a0f7256ae841deb7
قاعدة البيانات: OpenAIRE