Association between enteral nutrition support and neurological outcome in patients with acute intracranial haemorrhage: A retrospective cohort study
العنوان: | Association between enteral nutrition support and neurological outcome in patients with acute intracranial haemorrhage: A retrospective cohort study |
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المؤلفون: | Yingting Xu, Xuandong Jiang, Weizhe Ru, Xuping Cheng, Yanfei Shen, Yongxia Hu, Kailei Du, Weimin Zhang |
المصدر: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019) |
بيانات النشر: | Nature Publishing Group UK, 2019. |
سنة النشر: | 2019 |
مصطلحات موضوعية: | 0301 basic medicine, Male, medicine.medical_specialty, lcsh:Medicine, Single Center, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Enteral Nutrition, Internal medicine, medicine, Humans, Nutrition disorders, 030212 general & internal medicine, lcsh:Science, Propensity Score, Retrospective Studies, 030109 nutrition & dietetics, Multidisciplinary, business.industry, lcsh:R, Glasgow Coma Scale, Retrospective cohort study, Odds ratio, Prognosis, Confidence interval, Parenteral nutrition, Treatment Outcome, Quartile, Propensity score matching, lcsh:Q, Female, Nervous System Diseases, business, Energy Intake, Intracranial Hemorrhages, Neurological disorders |
الوصف: | Association between the amount of enteral nutrition (EN) caloric intake and Glasgow coma scale scores at discharge (GCSdis) in intracranial haemorrhage (ICH) was retrospectively investigated in 230 patients in a single center from 2015 and 2017. GCSdis was used as a dichotomous outcome (≤8 or >8: 56/230 vs. 174/230) and its association with the amount of EN caloric intake within 48 hours was analysed in four logistic models. Model 1 used EN as a continuous variable and showed association with favourable GCSdis (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01–1.08). Models 2 and 3 categorized EN into two (≤25 and >25 kcal/kg/48 hrs) and three caloric intake levels (≤10, 10~25, and >25 kcal/kg/48 hrs) respectively, and compared them with the lowest level; highest EN level associated with favourable GCSdis in both model 2 (OR, 2.77; 95%CI, 1.25–6.13) and 3 (OR, 4.68; 95%CI, 1.61–13.61). Model 4 transformed EN into four quartiles (Q1-Q4). Compared to Q1, OR increased stepwise from Q2 (OR 1.80, 95%CI 0.59–5.44) to Q4 (OR 4.71, 95%CI 1.49–14.80). Propensity score matching analysis of 69 matched pairs demonstrated consistent findings. In the early stage of ICH, increased EN was associated with favourable GCSdis. |
اللغة: | English |
تدمد: | 2045-2322 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71578c30a6698f1d561d86ed21e9952d http://europepmc.org/articles/PMC6848122 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....71578c30a6698f1d561d86ed21e9952d |
قاعدة البيانات: | OpenAIRE |
تدمد: | 20452322 |
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