Rice Bran Oil Decreases Total and LDL Cholesterol in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
| العنوان: | Rice Bran Oil Decreases Total and LDL Cholesterol in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials |
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| المؤلفون: | F. Siassi, Leila Azadbakht, Mohammad Hossein Rouhani, Nahid Ramezani Jolfaie, Pamela J. Surkan |
| المصدر: | Hormone and Metabolic Research. 48:417-426 |
| بيانات النشر: | Georg Thieme Verlag KG, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, medicine.medical_specialty, Apolipoprotein B, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Blood lipids, Biochemistry, Rice Bran Oil, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Endocrinology, High-density lipoprotein, Randomized controlled trial, law, Internal medicine, Humans, Plant Oils, Medicine, Food science, Triglycerides, Randomized Controlled Trials as Topic, 030109 nutrition & dietetics, biology, Cholesterol, business.industry, Cholesterol, HDL, Biochemistry (medical), Rice bran oil, nutritional and metabolic diseases, food and beverages, Cholesterol, LDL, General Medicine, Middle Aged, Biotechnology, Clinical trial, chemistry, Meta-analysis, biology.protein, Female, lipids (amino acids, peptides, and proteins), business |
| الوصف: | Cardiovascular disease (CVD) has become a concerning health problem because of its increasing prevalence. Vegetable oils such as rice bran oil may improve blood lipids, risk factors for CVD. We performed a systematic review and meta-analysis to identify and quantify the effects of rice bran oil on lipid profiles in humans. Literature databases (Pubmed, Scopus, Science Direct, Proquest, Ovid, and Google Scholar) were systematically searched until the end of November 2015, with no restrictions regarding study design, time, or language. The variables extracted for the meta-analysis included low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), total cholesterol (TC), triacylglycerol (TAG), VLDL-C, apoA, apoB, Lp(a), TC/HDL-C, and LDL-C/HDL-C. From 415 identified articles, 11 randomized controlled trials met the eligibility criteria and were included in our review. Rice bran oil consumption resulted in a significant decrease in concentrations of LDL-C (-6.91 mg/dl, 95% CI, -10.24 to -3.57; p0.001) and TC (-12.65 mg/dl; 95% CI, -18.04 to -7.27; p0.001). The increase in HDL-C levels were considerable only in men (6.65 mg/dl; 95% CI, 2.38-10.92; p=0.002). Results of our meta-analysis provided no evidence of a significant effekt of rice bran oil on other lipid profile components. In conclusion, consumption of rice bran oil can reduce LDL-C and TC concentrations, which may lead to prevention and control of CVD. It also has favorable effects on HDL-C concentrations in men. However, changes related to other lipid profile components are not considerable. |
| تدمد: | 1439-4286 0018-5043 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d675aef7d5c8f0740c5f03bb775015 https://doi.org/10.1055/s-0042-105748 |
| رقم الأكسشن: | edsair.doi.dedup.....71d675aef7d5c8f0740c5f03bb775015 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14394286 00185043 |
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