Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy
| العنوان: | Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy |
|---|---|
| المؤلفون: | Friedemann Paul, Frederike C. Oertel, Hanna Zimmermann, Alexander U. Brandt |
| المصدر: | The EPMA Journal |
| بيانات النشر: | Springer International Publishing, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, genetic structures, Tomography, optical coherence, Central nervous system, Optic neuritis, Review, Diagnosis, differential, Retina, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Optical coherence tomography, Drug Discovery, medicine, Disease progression, Neuromyelitis optica, medicine.diagnostic_test, business.industry, Health Policy, Biochemistry (medical), Retinal, medicine.disease, eye diseases, 030104 developmental biology, medicine.anatomical_structure, chemistry, Vision disorders, Optic nerve, Radiology, sense organs, Differential diagnosis, business, 030217 neurology & neurosurgery |
| الوصف: | Neuromyelitis optica spectrum disorders (NMOSD) are mostly relapsing inflammatory disorders of the central nervous system (CNS). Optic neuritis (ON) is the first NMOSD-related clinical event in 55% of the patients, which causes damage to the optic nerve and leads to visual impairment. Retinal optical coherence tomography (OCT) has emerged as a promising method for diagnosis of NMOSD and potential individual monitoring of disease course and severity. OCT not only detects damage to the afferent visual system caused by ON but potentially also NMOSD-specific intraretinal pathology, i.e. astrocytopathy. This article summarizes retinal involvement in NMOSD and reviews OCT methods that could be used now and in the future, for differential diagnosis, for monitoring of disease course, and in clinical trials. |
| اللغة: | English |
| تدمد: | 1878-5085 1878-5077 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72657e06d532e4326f349117d85a3ae2 http://europepmc.org/articles/PMC5833887 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....72657e06d532e4326f349117d85a3ae2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18785085 18785077 |
|---|