Preclinical and histological study of boron-containing compounds hydrogels on experimental model of periodontal disease
| العنوان: | Preclinical and histological study of boron-containing compounds hydrogels on experimental model of periodontal disease |
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| المؤلفون: | Melania Olimpia Cojocaru, Horia Octavian Manolea, Mihai Popescu, Ion Romulus Scorei, Daniel Alin Olimid, Ioana Mitruţ, Andrei Biţă, George Dan Mogoşanu |
| المصدر: | Romanian Journal of Morphology and Embryology |
| بيانات النشر: | Societatea Romana de Morfologie, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Embryology, Pathology, medicine.medical_specialty, experimental model, periodontal disease, Alveolar Bone Loss, Inflammation, Pathology and Forensic Medicine, Periodontal disease, Boron containing, Calcium Fructoborate, medicine, Animals, Rats, Wistar, Boron, Periodontitis, Original Paper, Experimental model, business.industry, Soft tissue, Hydrogels, Cell Biology, General Medicine, Models, Theoretical, medicine.disease, Oral tissue, Rats, inflammation, Self-healing hydrogels, ligature, Boric Acid, medicine.symptom, business, Developmental Biology |
| الوصف: | Periodontitis is a disease that affects a wide group of people, and there has been an increased interest in the research of finding useful materials that help reduce inflammation and the further loss of tissue. In this study, we have tested a boron-containing compound (BCC) Calcium Fructoborate (CaFB) and Boric Acid (BA) hydrogels on the gingival level on Wistar rats. First, we have induced the periodontal disease at the lower incisors, we have applied the hydrogels and after a week, we have euthanized the rats. Next, the oral soft tissue reaction was clinically and then histologically investigated. Our study has shown good clinical response of the oral tissue, and we have noticed lower levels of inflammation on the experimental groups treated with the BCCs hydrogels. Despite the generally good response of the biological structures to the presence of BA and CaFB on periodontal level, more scientifically proved information is needed to obtain the desired biological responses in all clinical situations. |
| تدمد: | 2066-8279 1220-0522 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fe952c1c50afee1fa2ee357200d9c6 https://doi.org/10.47162/rjme.62.1.21 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....72fe952c1c50afee1fa2ee357200d9c6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20668279 12200522 |
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