Fractal Analysis of Nuclear Medicine Images for the Diagnosis of Pulmonary Emphysema
| العنوان: | Fractal Analysis of Nuclear Medicine Images for the Diagnosis of Pulmonary Emphysema |
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| المؤلفون: | Yih-Hwen Huang, Hsiao Wen Chung |
| المصدر: | American Journal of Roentgenology. 174:1055-1059 |
| بيانات النشر: | American Roentgen Ray Society, 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | business.industry, Pulmonary emphysema, Image processing, General Medicine, Fractal dimension, Fractal analysis, Regression, Fractals, Fractal, Pulmonary Emphysema, Humans, Area ratio, Medicine, Radiology, Nuclear Medicine and imaging, Radionuclide imaging, Radionuclide Imaging, Nuclear medicine, business, Retrospective Studies |
| الوصف: | The purpose of this study was to investigate, on images obtained in nuclear medicine examinations, the physical meanings and consequent implications of fractal analysis developed in a recent study that was reported to be effective in quantifying the heterogeneous distribution of carbon particle radioaerosol in the lungs.Fractal dimensions were computed for 108 sets of radionuclide imaging data from 28 patients according to the methods in a previous report, and were then correlated with the ratio of tissue areas segmented at two thresholds (15% and 35% of maximal radioactivity).Fractal dimension was found to linearly correlate with the ratio natural logarithm of tissue areas segmented at two different threshold levels (n = 108, r = 0.999), with regression slope accurately predicted (error = 0.06%). Bland-Altman analysis showed that fractal dimensions ranging from 0.2 to 1.9 can be explained by this area ratio with disagreement of only 5.13% at two standard deviations; thus, fractal dimension seems to be an over-simplified parameter unrelated to spatial heterogeneity of radioaerosol distribution.The analysis of this study suggested that the fractal dimension defined in a previous report was limited to the indication of the percentage area of low-radioactivity regions with respect to total tissue area in the image. Because the fractal dimension partially reflects, but is not specific to, a certain degree of focal spots of low radioactivity, we suggest using fractal analysis in clinical practice only with careful control and thorough understanding of the physical meanings. |
| تدمد: | 1546-3141 0361-803X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739ce48929b0f3444623eda835755bf4 https://doi.org/10.2214/ajr.174.4.1741055 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....739ce48929b0f3444623eda835755bf4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15463141 0361803X |
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