التفاصيل البيبلوغرافية
العنوان:
A framework for human microbiome research
المؤلفون:
Rosamond Rhodes , Asif T. Chinwalla , Tessa Madden , Ashlee M. Earl , Maria C. Rivera , Candace N. Farmer , Jonathan M. Goldberg , Karthik Kota , Victor Felix , Nicholas B. King , Shibu Yooseph , Erica Sodergren , Monika Bihan , Martin J. Blaser , Dirk Gevers , Dan Knights , Pamela Sankar , Anup Mahurkar , Heather Huot Creasy , Veena Bhonagiri , Thomas M. Schmidt , Curtis Huttenhower , Mina Rho , Todd J. Treangen , Thomas J. Sharpton , I. Min A. Chen , Bo Liu , Sarah K. Highlander , Catherine C. Davis , Susan M. Huse , Richard A. Gibbs , Noam J. Davidovics , Patricio S. La Rosa , Carsten Russ , Wesley C. Warren , Richard K. Wilson , Patrick Minx , Jean E. McEwen , Alyxandria M. Schubert , Scott Anderson , Bonnie P. Youmans , Jamison McCorrison , Kathie A. Mihindukulasuriya , Vandita Joshi , Peter J. Mannon , Brandi L. Cantarel , Joseph F. Petrosino , Jack D. Sobel , Chandri Yandava , Sharvari Gujja , Janet K. Jansson , David J. Dooling , Daniel McDonald , Rob Knight , Granger G. Sutton , Gary C. Armitage , Larry J. Forney , Robert S. Fulton , Yuan Qing Wu , Jonathan Crabtree , Susan Kinder-Haake , Lu Wang , Liang Ye , Victor M. Markowitz , Narmada Shenoy , Elizabeth A. Lobos , Ruth M. Farrell , Tatiana A. Vishnivetskaya , Patrick S. G. Chain , Jacques Ravel , Katherine H. Huang , Sergey Koren , Yan Ding , Christina Giblin , Jason R. Miller , Michelle G. Giglio , Gina A. Simone , Chad Nusbaum , Lynn M. Schriml , Matthew C. Ross , Daniel D. Sommer , Sandra L. Lee , Theresa A. Hepburn , Michael Holder , Shaila Chhibba , Patrick D. Schloss , Omry Koren , Lan Zhang , Catrina Fronick , Richard R. Sharp , Diana Tabbaa , Yuzhen Ye , Dennis C. Friedrich , Christie Kovar , Owen White , A. Scott Durkin , Michael Feldgarden , Gary L. Andersen , Makedonka Mitreva , Todd Wylie , Nihar U. Sheth , Sheila Fisher , John Martin , Jose C. Clemente , Xiang Qin , James Versalovic , Dana A. Busam , Bruce W. Birren , Jeremy Zucker , Yu-Hui Rogers , Shannon Dugan , Kristine M. Wylie , Katherine P. Lemon , Floyd E. Dewhirst , Nicola Segata , Konstantinos Liolios , Anthony A. Fodor , Elizabeth L. Appelbaum , Ramana Madupu , W. Michael Dunne , Katherine S. Pollard , Leslie Foster , Olukemi O. Abolude , Yue Liu , Nikos C. Kyrpides , Christopher Wellington , Yanjiao Zhou , Lita M. Proctor , Tsegahiwot Belachew , Mircea Podar , Julia A. Segre , Holli A. Hamilton , Aye Wollam , Paul Spicer , Lei Chen , Sarah Young , Beltran Rodriguez-Mueller , Todd Z. DeSantis , Sean M. Sykes , Toby Bloom , Kelvin Li , Shane Canon , Catherine Jordan , Manolito Torralba , Brandi Herter , R. Dwayne Lunsford , Krishna Palaniappan , Jeroen Raes , Hongyu Gao , Barbara A. Methé , Kjersti Aagaard , Amy L. McGuire , Jonathan Friedman , Matthew D. Pearson , Jason Walker , Mary A. Cutting , Jonathan H. Badger , Diane E. Hoffmann , Tulin Ayvaz , Michael Fitzgerald , Brian J. Haas , Ravi Sanka , Doyle V. Ward , Kris A. Wetterstrand , Mark A. Watson , Christopher Smillie , Lucinda Fulton , Zhengyuan Wang , Lisa Begg , James R. White , Konstantinos Mavrommatis , Lucia Alvarado , Pamela McInnes , Emily L. Harris , Harindra Arachchi , Craig Pohl , Catherine A. Lozupone , Ruth E. Ley , Clinton Howarth , Yiming Zhu , Huaiyang Jiang , Gregory A. Buck , Carl C. Baker , Kimberley D. Delehaunty , Cristyn Kells , Katarzyna Wilczek-Boney , Kim C. Worley , Cesar Arze , J. Fah Sathirapongsasuti , Carolyn Deal , Sandra W. Clifton , Ken Chu , Rachel L. Erlich , Elaine R. Mardis , Cecil M. Lewis , Niall Lennon , Margaret Priest , Scott T. Kelley , Kymberlie Hallsworth-Pepin , Jane Peterson , Allison D. Griggs , Michelle O'Laughlin , Heidi H. Kong , Joshua Orvis , Maria Y. Giovanni , Sahar Abubucker , Dawn Ciulla , Sean Conlan , Chien Chi Lo , Antonio Gonzalez , Georgia Giannoukos , Jennifer R. Wortman , Paul Brooks , Jacques Izard , Chad Tomlinson , Donna M. Muzny , Shital M. Patel , Eric J. Alm , George M. Weinstock , Irene Newsham , Jeffrey G. Reid , Karoline Faust , Qiandong Zeng , Elena Deych , Nathalia Garcia , Mathangi Thiagarajan , James A. Katancik , Vivien Bonazzi , Robert C. Edgar , Christian J. Buhay , Indresh Singh , Johannes B. Goll , Ioanna Pagani , Vincent Magrini , Wendy A. Keitel , Emma Allen-Vercoe , Teena Mehta , Jeffery A. Schloss , William D. Shannon , Mihai Pop , Matthew B. Scholz , Valentina Di Francesco , Rebecca Truty , Karen E. Nelson , Kevin Riehle , Lora Lewis , Joseph L. Campbell , Laurie Zoloth
المساهمون:
Massachusetts Institute of Technology. Computational and Systems Biology Program, Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Civil and Environmental Engineering, Friedman, Jonathan, Smillie, Chris Scott, Alm, Eric J.
المصدر:
Nature
سنة النشر:
2012
مصطلحات موضوعية:
Adult , Male , Adolescent , Statistics as Topic , Population , Computational biology , Biology , Genome , Article , Young Adult , 03 medical and health sciences , Human health , 0302 clinical medicine , RNA, Ribosomal, 16S , Humans , Microbiome , education , 030304 developmental biology , Genetics , 0303 health sciences , education.field_of_study , Multidisciplinary , Bacteria , Human microbiome , Reference Standards , Metagenomics , 030220 oncology & carcinogenesis , Earth Microbiome Project , Metagenome , Female , Human Microbiome Project
الوصف:
A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. Here we present resources from a population of 242 healthy adults sampled at 15 or 18 body sites up to three times, which have generated 5,177 microbial taxonomic profiles from 16S ribosomal RNA genes and over 3.5 terabases of metagenomic sequence so far. In parallel, approximately 800 reference strains isolated from the human body have been sequenced. Collectively, these data represent the largest resource describing the abundance and variety of the human microbiome, while providing a framework for current and future studies.
وصف الملف:
application/pdf
اللغة:
English
تدمد:
1476-4687
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743da601f2767f68f0580b85d723fa0a http://europepmc.org/articles/PMC3377744
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....743da601f2767f68f0580b85d723fa0a
قاعدة البيانات:
OpenAIRE
