Adult Celiac Disease Associated with HLA-DRw3 and -DRw7
العنوان: | Adult Celiac Disease Associated with HLA-DRw3 and -DRw7 |
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المؤلفون: | Y. Minaire, Gebuhrer L, J. Bertrand, Descos L, H. Percebois, Betuel H |
المصدر: | Tissue Antigens. 15:231-238 |
بيانات النشر: | Wiley, 2008. |
سنة النشر: | 2008 |
مصطلحات موضوعية: | Adult, Male, Adolescent, Genetic Linkage, Adult celiac disease, Immunology, High linkage disequilibrium, Human leukocyte antigen, Disease, Cross Reactions, Haploidy, Biochemistry, Absorption, Antigen, Genetics, Humans, Immunology and Allergy, Medicine, Typing, High prevalence, Adult patients, business.industry, Histocompatibility Antigens Class II, General Medicine, Celiac Disease, Female, France, business |
الوصف: | Celiac disease (CD), which occurs in Europe with varying frequency, is known to be associated with HLA-B8 and even more strongly with HLA-Dw3 because of the high linkage disequilibrium between these two antigens. After typing for HLA-A, -B and -DR antigens in adult patients with CD, we can confirm the high prevalence of B8 (72.7%) and of DRw3 (63.7%). However we find that DRw7 is also significantly increased (54.5%); DRw3 and DRw7, taken together, represent 86% of our 22 patients. |
تدمد: | 1399-0039 0001-2815 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ce8f993ee38c2bfa79f2ca04b37f6a https://doi.org/10.1111/j.1399-0039.1980.tb00912.x |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....74ce8f993ee38c2bfa79f2ca04b37f6a |
قاعدة البيانات: | OpenAIRE |
تدمد: | 13990039 00012815 |
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