The Economic Burden of Thromboembolic Events Among Patients with Immune-Mediated Diseases
| العنوان: | The Economic Burden of Thromboembolic Events Among Patients with Immune-Mediated Diseases |
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| المؤلفون: | Juliana Setyawan, Emma Billmyer, Fan Mu, Andres Yarur, Miriam L. Zichlin, Hongbo Yang, Nathaniel Downes, Nassir Azimi, Vibeke Strand |
| المصدر: | Advances in Therapy |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, Thromboembolic events, Ischemic stroke, Cost, Pulmonary embolism, Financial Stress, Economic burden, Health Care Costs, General Medicine, Middle Aged, Medicare, United States, Myocardial infarction, Deep vein thrombosis, Thromboembolism, Humans, Female, Pharmacology (medical), Immune-mediated diseases, Original Research, Aged, Retrospective Studies |
| الوصف: | Introduction Thromboembolic events (TEs) are associated with considerable costs. However, there is a paucity of evidence quantifying the economic burden associated with TEs among patients with immune-mediated diseases (IMDs). Methods This retrospective cohort study used the IBM MarketScan® Commercial and Medicare Supplemental Claims databases (2014–2018). Commercially insured adults with IMDs were classified into two cohorts based on diagnosis of TEs (deep vein thrombosis, pulmonary embolism, ischemic stroke, myocardial infarction). Patients in the TE cohort were matched on type of IMD, age, sex, and year of diagnosis to patients in the no TE cohort. In the TE cohort, the index date was the date of first TE following first IMD diagnosis. In the no TE cohort, the index date was assigned so the duration from first IMD diagnosis to index date matched the duration for the corresponding patient in the TE cohort. All-cause total healthcare costs were compared between cohorts in the 30-day and 1-year periods following the index date (inclusive). Unadjusted comparisons were conducted using Wilcoxon signed-rank tests. Adjusted results were estimated using generalized estimating equations with robust sandwich estimator. Results Overall, 9681 matched patients were included in each cohort (mean age 61.1 years; 63.7% female). The TE cohort had higher proportions of comorbidities than the no TE cohort (Charlson Comorbidity Index [1.5 vs. 0.9]; p |
| تدمد: | 1865-8652 0741-238X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fceef168cb0923614b18081cefcdef https://doi.org/10.1007/s12325-021-02004-1 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....74fceef168cb0923614b18081cefcdef |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18658652 0741238X |
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