Bioinspired cilia arrays with programmable nonreciprocal motion and metachronal coordination
| العنوان: | Bioinspired cilia arrays with programmable nonreciprocal motion and metachronal coordination |
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| المؤلفون: | Guo Zhan Lum, Metin Sitti, Wenqi Hu, Rongjing Zhang, Patrick Onck, Ziyu Ren, Xiaoguang Dong |
| المساهمون: | Micromechanics, Sitti, Metin (ORCID 0000-0001-8249-3854 & YÖK ID 297104), Dong, Xiaoguang, Lum, Guo Zhan, Hu, Wenqi, Zhang, Rongjing, Ren, Ziyu, Onck, Patrick R., School of Medicine, College of Engineering, Department of Mechanical Engineering, School of Mechanical and Aerospace Engineering |
| المصدر: | Science Advances, 6(45):eabc9323. AMER ASSOC ADVANCEMENT SCIENCE Science Advances Science Advances, 6 (45) |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Reynolds Number, Acoustics, Materials Science, Microfluidics, 02 engineering and technology, Multidisciplinary sciences, Quantitative Biology::Cell Behavior, Physics::Fluid Dynamics, Transport, Flow, Microorganisms, Paramecium, Propulsion, Patterns, Robots, 03 medical and health sciences, symbols.namesake, Engineering, Fluid dynamics, Research Articles, 030304 developmental biology, Complex fluid, Physics, Physics::Biological Physics, 0303 health sciences, Multidisciplinary, Miniature Instruments, Cilium, SciAdv r-articles, Reynolds number, 021001 nanoscience & nanotechnology, Mechanical engineering [Engineering], symbols, 0210 nano-technology, Research Article |
| الوصف: | Coordinated nonreciprocal dynamics in biological cilia is essential to many living systems, where the emergentmetachronal waves of cilia have been hypothesized to enhance net fluid flows at low Reynolds numbers (Re). Experimental investigation of this hypothesis is critical but remains challenging. Here, we report soft miniature devices with both ciliary nonreciprocal motion and metachronal coordination and use them to investigate the quantitative relationship between metachronal coordination and the induced fluid flow. We found that only antiplectic metachronal waves with specific wave vectors could enhance fluid flows compared with the synchronized case. These findings further enable various bioinspired cilia arrays with unique functionalities of pumping and mixing viscous synthetic and biological complex fluids at low Re. Our design method and developed soft miniature devices provide unprecedented opportunities for studying ciliary biomechanics and creating cilia-inspired wireless microfluidic pumping, object manipulation and lab- and organ-on-a-chip devices, mobile microrobots, and bioengineering systems. Science Advances, 6 (45) ISSN:2375-2548 |
| وصف الملف: | application/pdf; application/application/pdf; pdf |
| اللغة: | English |
| تدمد: | 2375-2548 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752f09a47493d4cdbed1327801c766d9 https://research.rug.nl/en/publications/537381a5-9175-4a9d-a220-9d08fe73cf04 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....752f09a47493d4cdbed1327801c766d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23752548 |
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