The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice
| العنوان: | The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice |
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| المؤلفون: | Lan, Bai, Yong-Li, Wang, Yan-Lin, Chen, Hu-Xiao, Li, Shi-Wei, Zhu, Yan, Liu, Zhong-Chen, Song, Sheng-Zhong, Duan |
| المصدر: | Journal of Clinical Periodontology. 49:1067-1078 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Liver Cirrhosis, Male, Microbiota, Alanine Transaminase, Actins, Methylene Blue, Hydroxyproline, Mice, Transforming Growth Factor beta, RNA, Ribosomal, 16S, Animals, Periodontics, Periodontitis, Azo Compounds, Carbon Tetrachloride |
| الوصف: | Periodontitis (PD) is the sixth most prevalent disease around the world and is involved in the development and progression of multiple systemic diseases. Previous studies have reported that PD may aggravate liver injuries. The objective of this study was to investigate whether and how PD affects liver fibrosis.Ligature-induced PD (LIP) was induced in male C57/B6J mice, and sub-gingival plaques (PL) from patients with PD were applied to mouse teeth. Liver fibrosis was induced by carbon tetrachloride (CClMice in the CClPD aggravates CCl |
| تدمد: | 1600-051X 0303-6979 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76008d2d63e6b044e8ce605dc1eb2d5a https://doi.org/10.1111/jcpe.13682 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....76008d2d63e6b044e8ce605dc1eb2d5a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1600051X 03036979 |
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