التفاصيل البيبلوغرافية
العنوان:
A five‐mRNA signature associated with post‐translational modifications can better predict recurrence and survival in cervical cancer
المؤلفون:
Lin Wang , Lin Zhao , Longyang Jiang , Qiang Zhang , Jia Bi , Lan Zhao , Qiutong Guan , Minjie Wei , Xueping Li , Mingyi Ju , Qian Wei , Aoshuang Qi
المصدر:
Journal of Cellular and Molecular Medicine
بيانات النشر:
Wiley, 2020.
سنة النشر:
2020
مصطلحات موضوعية:
CD4-Positive T-Lymphocytes , 0301 basic medicine , Oncology , medicine.medical_specialty , cervical cancer , Human Protein Atlas , tumour‐infiltrating immune cells , Uterine Cervical Neoplasms , Kaplan-Meier Estimate , Lymphocyte Activation , 03 medical and health sciences , 0302 clinical medicine , Internal medicine , Databases, Genetic , Humans , Medicine , Effective treatment , post‐translational modifications , RNA, Messenger , Cervical cancer , Messenger RNA , business.industry , Gene Expression Profiling , CD4+ Memory T Cell , High mortality , Hazard ratio , biomarkers , Reproducibility of Results , Molecular Sequence Annotation , Original Articles , Cell Biology , Middle Aged , Prognosis , medicine.disease , Progression-Free Survival , Gene Expression Regulation, Neoplastic , 030104 developmental biology , 030220 oncology & carcinogenesis , Posttranslational modification , Molecular Medicine , Original Article , Female , activated CD4 memory T cell , Neoplasm Recurrence, Local , business , Immunologic Memory , Protein Processing, Post-Translational
الوصف:
High mortality of patients with cervical cancer (CC) stresses the imperative of prognostic biomarkers for CC patients. Additionally, the vital status of post‐translational modifications (PTMs) in the progression of cancers has been reported by numerous researches. Therefore, the purpose of this research was to dig a prognostic signature correlated with PTMs for CC. We built a five‐mRNA (GALNTL6, ARSE, DPAGT1, GANAB and FURIN) prognostic signature associated with PTMs to predict both disease‐free survival (DFS) (hazard ratio [HR] = 3.967, 95% CI = 1.985‐7.927; P
تدمد:
1582-4934 1582-1838
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e3befb2d8ba90cf6fc746b21a723e6 https://doi.org/10.1111/jcmm.15270
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....76e3befb2d8ba90cf6fc746b21a723e6
قاعدة البيانات:
OpenAIRE