Tolerability of palbociclib in younger and older patients with advanced breast cancer

التفاصيل البيبلوغرافية
العنوان: Tolerability of palbociclib in younger and older patients with advanced breast cancer
المؤلفون: Ryan Kemper, Allison M. Deal, Kelly Brunk, Taylor Dennison, Hillary M. Heiling, Aimee Faso, Daniel J. Crona
المصدر: Journal of Oncology Pharmacy Practice. 29:96-104
بيانات النشر: SAGE Publications, 2021.
سنة النشر: 2021
مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Kinase, Advanced breast, Cancer, Palbociclib, Neutropenia, medicine.disease, Tolerability, Older patients, Internal medicine, medicine, Pharmacology (medical), business, Hormone
الوصف: Introduction Palbociclib is a small-molecule cyclin-dependent kinase 4/6 inhibitor used to treat hormone receptor-positive, human epidermal growth factor receptor-2 negative advanced breast cancer. Patient-specific factors impacting dose reductions or discontinuations are unknown. Methods The primary objective was to evaluate the association of age (Results Among the 107 patients included, younger patients were less likely than older patients to have a palbociclib starting dose Conclusions Age (
تدمد: 1477-092X
1078-1552
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bfd7124711109dfa9a43710558bbd8
https://doi.org/10.1177/10781552211053639
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....77bfd7124711109dfa9a43710558bbd8
قاعدة البيانات: OpenAIRE