Biomarker-based MicroRNA Therapeutic Strategies for Hepatocellular Carcinoma
| العنوان: | Biomarker-based MicroRNA Therapeutic Strategies for Hepatocellular Carcinoma |
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| المؤلفون: | Min Yao, Li Wang, Dengfu Yao, Yao Yao, Hong-Bing Gu |
| المصدر: | Journal of Clinical and Translational Hepatology |
| بيانات النشر: | XIA & HE Publishing Ltd, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Programmed cell death, Hepatology, Molecular target, business.industry, Hepatocellular carcinoma, MicroRNA, Review Article, medicine.disease_cause, Bioinformatics, medicine.disease, Biomarker (cell), Malignant transformation, law.invention, Key factors, law, microRNA, medicine, Suppressor, Therapy, Carcinogenesis, business |
| الوصف: | Recently, microRNAs (miRNAs) have emerged as key factors involved in a series of biological processes, ranging from embryogenesis to programmed cell death. Its link to aberrant expression profiles has rendered it a potentially attractive tool for the diagnosis, prognosis, or treatment of various diseases. Accumulating evidence has indicated that miRNAs act as tumor suppressors in hepatocyte malignant transformation by regulating development, differentiation, proliferation, and tumorigenesis. Here, we summarize recent progress in the development of novel biomarker-based miRNA therapeutic strategies for hepatocellular carcinoma (HCC). |
| اللغة: | English |
| تدمد: | 2310-8819 2225-0719 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788875ee1b3c8a88da4a435e5b26c6cb http://europepmc.org/articles/PMC4521238 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....788875ee1b3c8a88da4a435e5b26c6cb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23108819 22250719 |
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