Three-dimensional imaging of spatio-temporal dynamics of small blood capillary network in the cortex based on optical coherence tomography: A review
| العنوان: | Three-dimensional imaging of spatio-temporal dynamics of small blood capillary network in the cortex based on optical coherence tomography: A review |
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| المؤلفون: | Jonghwan Lee, Collin Polucha, Jang Hoon Lee, Fangjian Xing |
| المصدر: | Journal of Innovative Optical Health Sciences, Vol 13, Iss 1, Pp 2030002-1-2030002-16 (2020) |
| بيانات النشر: | World Scientific Pub Co Pte Ltd, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Computer science, Biomedical Engineering, Medicine (miscellaneous), lcsh:Technology, 01 natural sciences, brain cortex, 010309 optics, Blood capillary, 03 medical and health sciences, oct, 0302 clinical medicine, Optical coherence tomography, Cortex (anatomy), 0103 physical sciences, medicine, blood flow, lcsh:QC350-467, angiography, micro-angiogram, medicine.diagnostic_test, lcsh:T, dynamics, Optical coherence tomography angiography, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Three dimensional imaging, medicine.anatomical_structure, Angiography, capillary vessel, Neuroscience research, lcsh:Optics. Light, 030217 neurology & neurosurgery, Preclinical imaging, Biomedical engineering |
| الوصف: | Optical coherence tomography angiography (OCTA) has emerged as an advanced in vivo imaging modality, which is widely used for the clinic ophthalmology and neuroscience research in the rodent brain cortex among others. Based on the high numerical aperture (NA) probing lens and the motion-corrected algorithms, a high-resolution imaging technique called OCT micro-angiography is applied to resolve the small blood capillary vessels ranging from 5[Formula: see text][Formula: see text]m to 10[Formula: see text][Formula: see text]m in diameter. As OCT-based techniques are recently evolving further from the structural imaging of capillaries toward spatio-temporal dynamic imaging of blood flow in capillaries, here we present a review on the latest techniques for the dynamic flow imaging. Studies on capillary blood flow using these techniques will help us better understand the roles of capillary blood flow for normal functioning of the brain as well as how it malfunctions in diseases. |
| تدمد: | 1793-7205 1793-5458 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b6fcd6a2a5d561fa70eb308d54a68c https://doi.org/10.1142/s1793545820300025 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....78b6fcd6a2a5d561fa70eb308d54a68c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17937205 17935458 |
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