Review article: obesity and colorectal cancer
| العنوان: | Review article: obesity and colorectal cancer |
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| المؤلفون: | Marc Bardou, Alexia Rouland, Myriam Martel, Romaric Loffroy, Alan N. Barkun, Nicolas Chapelle |
| المصدر: | Alimentary Pharmacology & Therapeutics. 56:407-418 |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Male, Hepatology, Rectal Neoplasms, Gastroenterology, Bariatric Surgery, Overweight, Body Mass Index, Pregnancy, Humans, Female, Pharmacology (medical), Obesity, Child, Colorectal Neoplasms |
| الوصف: | Obesity is a growing global public health problem. More than half the European and North American population is overweight or obese. Colon and rectum cancers are still the second leading cause of cancer death worldwide, and epidemiological data support an association between obesity and colorectal cancers (CRCs).To review the literature on CRC epidemiology in obese subjects, assessing the effects of obesity, including childhood or maternal obesity, on CRC, diagnosis, management, and prognosis, and discussing targeted prophylactic measures.We searched PubMed for obesity/overweight/metabolic syndrome and CRC. Other key words included 'staging', 'screening', 'treatment', 'weight loss', 'bariatric surgery' and 'chemotherapy'.In Europe, about 11% of CRCs are attributed to overweight and obesity. Epidemiological data suggest that obesity is associated with a 30%-70% increased risk of colon cancer in men, the association being less consistent in women. Visceral fat or abdominal obesity seems to be of greater concern than subcutaneous fat obesity, and any 1 kg/mDespite a growing body of evidence linking obesity to CRC, many questions remain unanswered, including whether we should screen patients with obesity earlier or propose prophylactic bariatric surgery for certain patients with obesity. |
| تدمد: | 1365-2036 0269-2813 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79371c3324f3210e5b661b50891d0f32 https://doi.org/10.1111/apt.17045 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....79371c3324f3210e5b661b50891d0f32 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652036 02692813 |
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