A Patient with Metastatic Microsatellite Instability-High Pancreatic Ductal Adenocarcinoma with a Prolonged Response to Single-Agent Pembrolizumab
| العنوان: | A Patient with Metastatic Microsatellite Instability-High Pancreatic Ductal Adenocarcinoma with a Prolonged Response to Single-Agent Pembrolizumab |
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| المؤلفون: | William T. Leslie, Annie A. Guedikian, Anita Sharko, Megan Randall |
| المصدر: | Case Reports in Oncology, Vol 14, Iss 3, Pp 1414-1417 (2021) Case Reports in Oncology |
| بيانات النشر: | Karger Publishers, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | metastatic pancreatic ductal adenocarcinoma, Pancreatic ductal adenocarcinoma, endocrine system diseases, programmed cell death protein 1 inhibitor, business.industry, mismatch repair deficiency, medicine.medical_treatment, Programmed Cell Death Protein 1 Inhibitor, Microsatellite instability, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Case Report, Pembrolizumab, Immunotherapy, medicine.disease, digestive system diseases, Oncology, medicine, Cancer research, MISMATCH REPAIR DEFICIENCY, Single agent, microsatellite instability, business, RC254-282 |
| الوصف: | Immunotherapy is an effective new approach in the treatment of many malignancies. However, pancreatic ductal adenocarcinoma (PDAC) does not usually respond to immunotherapy. We discuss the case of a patient with metastatic microsatellite instability-high PDAC who had a prolonged response to single-agent pembrolizumab for almost 3 years. |
| اللغة: | English |
| تدمد: | 1662-6575 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796dde4ffdef94f96cc86006f437f23f https://www.karger.com/Article/FullText/519181 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....796dde4ffdef94f96cc86006f437f23f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16626575 |
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