British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008
| العنوان: | British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008 |
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| المؤلفون: | John P. Walsh, Ian S. Williams, Brian Gazzard, Abdel Babiker, Andrew N. Phillips, Margaret A. Johnson, Gary Brough, Duncan Churchill, Anna Maria Geretti, Saye Khoo, Barry Peters, Devaki Nair, Gary Brook, Anton Pozniak, Clifford Leen, Ben Cromarty, Marta Boffito, Satyajit Das, Ed Wilkins, Martin Fisher, M Youle, Jane Anderson, Andrew L. Freedman, Deenan Pillay, Matthew Williams |
| المصدر: | HIV Medicine. 9:563-608 |
| بيانات النشر: | Wiley, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | medicine.medical_specialty, Inclusion (disability rights), business.industry, Surrogate endpoint, Health Policy, MEDLINE, Salvage therapy, HIV Infections, Guideline, law.invention, Infectious Diseases, Anti-Retroviral Agents, Randomized controlled trial, law, Antiretroviral Therapy, Highly Active, Family medicine, Immunology, HIV-1, Humans, Medicine, Pharmacology (medical), business, Association (psychology), Risk assessment |
| الوصف: | The 2008 BHIVA Guidelines have been updated to incorporate all the new relevant information (including presentations at the 15th Conference on Retroviruses and Opportunistic Infections 2008) since the last iteration. The guidelines follow the methodology outlined below and all the peer-reviewed publications and important, potentially treatment-changing abstracts from the last 2 years have been reviewed. The translation of data into clinical practice is often difficult even with the best possible evidence (i.e. two randomized controlled trials) because of trial design, inclusion criteria and precise surrogate marker endpoints (see Appendix). The recommendations based upon expert opinion have the least good evidence but perhaps provide an important reason for writing the guidelines to produce a consensual opinion about current practice. It must, however, be appreciated that such opinion is often wrong and should not stifle research to challenge it. Similarly, although the Writing Group seeks to provide guidelines to optimize treatment, such care needs to be individualized and we have not constructed a document that we would wish to see used as a ‘standard’ for litigation. |
| تدمد: | 1468-1293 1464-2662 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797252f7225529f47df004c880085ee3 https://doi.org/10.1111/j.1468-1293.2008.00636.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....797252f7225529f47df004c880085ee3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14681293 14642662 |
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