Prognostic value of cardiopulmonary exercise test after heart transplantation
| العنوان: | Prognostic value of cardiopulmonary exercise test after heart transplantation |
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| المؤلفون: | Emiliano Rossi, Juan Lagoria, Ricardo Marenchino, Guillermo Cornejo, Diego Iglesias, Leandro Barbagelata, César Belziti, Norberto Vulcano, Walter Masson, Hector Ventura, Mishel Mora, Rodolfo Pizarro |
| المصدر: | Clinical Transplantation. 35 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, medicine.medical_treatment, Oxygen pulse, 030230 surgery, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Cardiopulmonary exercise test, Internal medicine, medicine, Clinical endpoint, Humans, Retrospective Studies, Heart transplantation, Transplantation, business.industry, Mean age, Cardiopulmonary exercise testing, Retrospective cohort study, Middle Aged, Prognosis, Exercise Test, Cardiology, Heart Transplantation, Female, 030211 gastroenterology & hepatology, business |
| الوصف: | Background The clinical utility of cardiopulmonary exercise testing (CPET) has not been extensively studied yet in heart transplantation (HTX) patients. Objective To analyze the predictive value of the CPET on hospitalizations and mortality in HTX recipients. Methods A retrospective cohort was performed from a secondary database. Patients >18 years with HTX who underwent a CPET between 3 and 12 months after transplantation were included. Time to the first primary endpoint (HTX-related hospitalization) was analyzed and adjusted using Cox proportional hazards regression model. Results A total of 122 patients (mean age 50.1 years, 77.0% men) were included. Fifty-seven patients (46.7%) had the primary endpoint. Peak VO2 (HR 0.95; CI95% 0.90-0.99, p=0.03), oxygen pulse (HR 0.57; CI95% 0.34-0.96, p=0.03) and predicted VO2 (HR 0.97; CI95% 0.96-0.99, p=0.002) were associated with the endpoint. We did not find a significant association between the other variables and the outcome. Conclusion In HTX recipients, peak VO2 , oxygen pulse and predicted VO2 were independently associated with hospitalizations at follow up. This article is protected by copyright. All rights reserved. |
| تدمد: | 1399-0012 0902-0063 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bc2c80f8201f7c8d173f6e1b2845a7 https://doi.org/10.1111/ctr.14387 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....79bc2c80f8201f7c8d173f6e1b2845a7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13990012 09020063 |
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