التفاصيل البيبلوغرافية
العنوان:
Insights into the cellular pharmacological properties of the BET-inhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models
المؤلفون:
Ramiro Vázquez , Carmen Kahatt , Maria E. Riveiro , Mohamed Bekradda , C. Gardin , Sarah Mackenzie , Patrice Herait , Eric Raymond , Esteban Cvitkovic , Elodie Odore , Lucile Astorgues-Xerri , Hervé Dombret , Francesco Bertoni , François Lokiec , Keyvan Rezai , Kay Noel , Marie-Magdelaine Coudé
المصدر:
Leukemia & Lymphoma . 60:3067-3070
بيانات النشر:
Informa UK Limited, 2019.
سنة النشر:
2019
مصطلحات موضوعية:
Cancer Research , Protein family , Antineoplastic Agents , Apoptosis , chemical and pharmacologic phenomena , medicine.disease_cause , complex mixtures , BET inhibitor , Mice , 03 medical and health sciences , 0302 clinical medicine , Cell Line, Tumor , Biomarkers, Tumor , medicine , Animals , Humans , Epigenetics , Mutation , biology , Chemistry , Cell Cycle , Proteins , Drug Synergism , hemic and immune systems , Hematology , medicine.disease , Xenograft Model Antitumor Assays , Small molecule , Bromodomain , Cell biology , Disease Models, Animal , Leukemia , Histone , Oncology , 030220 oncology & carcinogenesis , biology.protein , bacteria , Acetanilides , Heterocyclic Compounds, 3-Ring , 030215 immunology
الوصف:
The bromodomain and extra-C-terminal domain (BET) protein family is a class of epigenetic readers that recognize acetyl-lysine residues of histones, and their targeting with small molecules is a no...
تدمد:
1029-2403
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bec83758d3dbef66f57d2e9cae6864 https://doi.org/10.1080/10428194.2019.1617860
رقم الأكسشن:
edsair.doi.dedup.....79bec83758d3dbef66f57d2e9cae6864
قاعدة البيانات:
OpenAIRE
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