Biosimilars are essential for sustainable healthcare systems; however, key challenges remain as seen with long-acting insulin analogues
| العنوان: | Biosimilars are essential for sustainable healthcare systems; however, key challenges remain as seen with long-acting insulin analogues |
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| المؤلفون: | Godman Brian, Tubic Biljana, Allocati Eleonora, Wladysiuk Magdalene, McTaggart Stuart, Kurdi Amanj, Haque Mainul, MacBride-Stewart Sean, Kalemeera Francis, Massele Amos, Hoxha Iris, Pekovic Vanda Markovic, Petrova Guenka, Tachkov Konstantin, Laius Ott, Harsanyi András, Inotai András, Jakupi Arianit, Henkuzens Svens, Garuoliené Kristina, Bonanno Patricia Vella, Rutkowski Jakub, Mardare Ileana, Fürst Jurij, Pontes Caridad, Zara Corinne, Pedrola Marta Turu, Akter Farhana, Kwon Hye-Young, Martin Antony P., Banzi Rita, Wale Janney, Gulbinovic Jolanta |
| المصدر: | Journal of applied pharmaceutical science, Madhya Pradesh : Open Science Publishers LLP, 2022, vol. 12, iss. 3, p. 55-72 |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Drug monitoring -- Europe, Biosimilar pharmaceuticals -- Europe, Drugs -- Prescribing -- Economic aspects, Insulin -- Costs, Drug accessibility -- Law and legislation -- Europe, Biosimilars, Demand-side measures, Europe, Health policies, Insulin glargine, Prices, Medicine (miscellaneous), Pharmacology (medical), General Pharmacology, Toxicology and Pharmaceutics |
| الوصف: | Sales of medicines continue to grow world-wide driven in part by increasing expenditures on biological medicines leading to concerns with the long-term sustainability of European healthcare systems. The increasing use of biosimilars at lower costs can potentially address this. However, there can be concerns with their prescribing. There are also concerns with biosimilar insulin glargine including concerns with different devices despite increasing sales of longacting insulin analogues worldwide. Consequently, a need to appraise the European biosimilar market incorporating measures to enhance their use including potential ways to increase the prescribing of biosimilars of insulin glargine at lower costs. Multiple approaches were used to undertake the study including researching measures to enhance biosimilar use and their impact across Europe. In addition, undertake cross national research on the utilization and expenditure of long-acting insulin analogues, which includes biosimilars, principally among Central and Eastern European countries. Multiple demand-side measures across the countries have enhanced the use of biosimilars. There was variable use of biosimilar insulin glargine 100 IU/ml driven by increasing use of patented 300 IU/ml formulations and small price differences between the originator and biosimilars in practice. Overall, multiple demand-side initiatives can appreciably increase biosimilar use benefiting all groups. Additional measures are needed to enhance future prescribing of long-acting biosimilar insulin analogues. peer-reviewed |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2231-3354 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a21960e1958dfeb42a855e3b2324314 https://repository.vu.lt/VU:ELABAPDB153217317&prefLang=en_US |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7a21960e1958dfeb42a855e3b2324314 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22313354 |
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