Efficacy of magnetic resonance urography in detecting renal scars in children with vesicoureteral reflux
| العنوان: | Efficacy of magnetic resonance urography in detecting renal scars in children with vesicoureteral reflux |
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| المؤلفون: | Recep Bayram, Selçuk Yüksel, Ali Koçyiğit, Ismail Yilmaz, Nevzat Karabulut |
| المصدر: | Pediatric Nephrology. 29:1215-1220 |
| بيانات النشر: | Springer Science and Business Media LLC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Nephrology, Voiding cystourethrogram, acute pyelonephritis, Kidney, urologic and male genital diseases, Scintigraphy, preschool child, scintigraphy, nuclear magnetic resonance imaging, Child, clinical article, predictive value, medicine.diagnostic_test, childhood disease, Vesicoureteral reflux, article, Urography, kidney scar, Magnetic Resonance Imaging, female, priority journal, nuclear magnetic resonance scanner, Child, Preschool, diagnostic accuracy, Female, Radiology, diagnostic use, medicine.drug, medicine.medical_specialty, Adolescent, Urinary system, comparative effectiveness, magnetic resonance urography, Cicatrix, image analysis, Internal medicine, medicine, follow up, Humans, controlled study, diagnostic test accuracy study, human, procedures, intermethod comparison, data analysis software, Vesico-Ureteral Reflux, micturition cystourethrography, business.industry, horseshoe kidney, Infant, ureterocele, Magnetic resonance imaging, Urinary tract infections, medicine.disease, succimer tc 99m, sensitivity and specificity, Dimercaptosuccinic acid, Technetium Tc 99m Dimercaptosuccinic Acid, Pediatrics, Perinatology and Child Health, pathology, business, Pyelogram |
| الوصف: | Background: The detection of renal scars is of paramount importance for optimal clinical management of patients with urinary tract infection (UTI) and vesicoureteral reflux (VUR). The aim of our study was to compare the efficacy of unenhanced magnetic resonance urography (MRU) and Tc-99m dimercaptosuccinic acid (Tc-DMSA) scintigraphy to dectect renal scars. Methods: Unenhanced MRU and Tc-DMSA scintigraphy were performed in 49 children (10 boys, 39 girls; mean age 7.4±4.2 years, range 1-15 years) with documented VUR. MR imaging scans were obtained within 7 days after voiding cystourethrogram (VCUG) and Tc-DMSA scintigraphy. The diagnostic performance of MRU in renal scar detection was calculated relative to that of the Tc-DMSA scan. Results: The renal scar detection rate of Tc-DMSA scintigraphy and unenhanced MRU in kidneys with VUR was 32.4 and 25.9%, respectively. The sensitivity and specificity of MRU in the detection of renal scars was 80 and 82.6% in kidneys with VUR, respectively. There was no statistically significant difference in lesion detection between MRU and Tc-DMSA scintigraphy (P >0.05).MRU and Tc-DMSA scintigraphy showed good agreement (κ = 0.60). Conclusions: Unenhanced MRU is a robust technique for the morphologic assessment of the urinary system and detection of renal scars. The lack of radiation and contrast material makes this technique a much safer alternative to scintigraphy in children with VUR, particularly in those who require follow-up scanning and, consequently, considerable radiation exposure. © IPNA 2014. |
| تدمد: | 1432-198X 0931-041X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a46e7522a7d2a778d9af97095c4d132 https://doi.org/10.1007/s00467-014-2766-y |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....7a46e7522a7d2a778d9af97095c4d132 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1432198X 0931041X |
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