Gestational age-dependent relationship between cerebral oxygen extraction and blood pressure
| العنوان: | Gestational age-dependent relationship between cerebral oxygen extraction and blood pressure |
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| المؤلفون: | Zachary A. Vesoulis, Steve M. Liao, Amit M. Mathur |
| المصدر: | Pediatric research |
| بيانات النشر: | Springer Science and Business Media LLC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Group based, chemistry.chemical_element, Blood Pressure, Gestational Age, Oxygen, Article, 03 medical and health sciences, 0302 clinical medicine, Intensive Care Units, Neonatal, 030225 pediatrics, Internal medicine, medicine, Humans, Autoregulation, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, Spectroscopy, Near-Infrared, business.industry, Infant, Newborn, Brain, Gestational age, ESTIMATED GESTATIONAL AGE, Blood pressure, chemistry, Pediatrics, Perinatology and Child Health, Cardiology, Female, Cerebral oxygen, business |
| الوصف: | BackgroundPremature infants may lack mature cerebrovascular autoregulatory function and fail to adapt oxygen extraction to decreasing systemic perfusion.MethodsInfants ≤28 weeks of gestational age (GA) were recruited. Systemic oxygen saturation (SpO2), mean arterial blood pressure (MABP), and cerebral saturation (near-infrared spectroscopy, SctO2) were measured continuously over the first 72 h. Resulting data underwent error-processing. For each remaining 10 m window, the mean MABP and fractional tissue oxygen extraction (FTOE) were calculated. The infants were divided into two groups (23-25 and 26-28 weeks). The median FTOE at low, medium, and high MABP values (empirically defined within each group based on the 25th and 75th centile) were compared between estimated gestational age (EGA) groups.ResultsSample n=68, mean±SD GA=25.5±1.3 weeks, and birthweight (BW)=823±195 g. The median FTOE in the more preterm group vs. more mature group was statistically different at lower value of MABP (P |
| تدمد: | 1530-0447 0031-3998 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b31c497bf03c43e35dbf3f1b58d69eb https://doi.org/10.1038/pr.2017.196 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7b31c497bf03c43e35dbf3f1b58d69eb |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15300447 00313998 |
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