Influence of a Novel Surface of Bioactive Implants on Osseointegration: A Comparative and Histomorfometric Correlation and Implant Stability Study in Minipigs
| العنوان: | Influence of a Novel Surface of Bioactive Implants on Osseointegration: A Comparative and Histomorfometric Correlation and Implant Stability Study in Minipigs |
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| المؤلفون: | José Vicente Ríos-Santos, Blanca Ríos-Carrasco, Francisco Javier Gil-Mur, Manuel Maria Romero-Ruiz, Mariano Herrero-Climent, Pedro Lázaro-Calvo |
| المصدر: | International Journal of Molecular Sciences Volume 20 Issue 9 International Journal of Molecular Sciences, Vol 20, Iss 9, p 2307 (2019) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Implant surface, Swine, Biocompatible Materials, 02 engineering and technology, Oral implants, lcsh:Chemistry, 0302 clinical medicine, immune system diseases, lcsh:QH301-705.5, Spectroscopy, implant surface, Ethics committee, hemic and immune systems, General Medicine, 021001 nanoscience & nanotechnology, Computer Science Applications, Bioactive Implants, minipigs, Swine, Miniature, Female, 0210 nano-technology, Histomorfometric analytic, Titanium, Materials science, Stability study, Surface Properties, chemistry.chemical_element, chemical and pharmacologic phenomena, Catalysis, Osseointegration, Bone and Bones, Article, Inorganic Chemistry, 03 medical and health sciences, stomatognathic system, Animals, Physical and Theoretical Chemistry, Molecular Biology, Rank correlation, Dental Implants, Organic Chemistry, 030206 dentistry, stomatognathic diseases, lcsh:Biology (General), lcsh:QD1-999, chemistry, Implant, Statistical correlation, Biomedical engineering |
| الوصف: | Purpose: The objective of this study was to assess the influence of a novel surface of dental implants (ContacTi® ) on the osseointegration process in a minipig model. The surface was compared with other existing surfaces on the market (SLA® and SLActive® ) by employing bone implant contact analysis (BIC) and implant stability. Method: Twelve minipigs were used with prior authorisation from an ethics committee. Three types of surfaces were tested: SLA® (sand-blasted acid-etched titanium), SLActive® (same but hydrophilic, performed under a nitrogen atmosphere), and ContacTi® (alumina particle bombardment of titanium, bioactivated when treated thermochemically) in 4.1 mm × 8 mm implants with internal connection and a polished neck. Twelve implants of each surface type (N = 36) were placed, sacrificing 1/3 of the animals at 2 weeks of placement, 1/3 at 4 weeks and the remaining 1/3 at 8 weeks. Numerical variables were compared with Analysis of Variance, and the correlation between ISQ and BIC was established with the Spearman&rsquo s rank correlation coefficient. Results: SLActive® and ContacTi® surfaces showed elevated osteoconductivity at 4 weeks, maintaining a similar evolution at 8 weeks (large amount of mature lamellar tissue with high maturity and bone quality). The SLA® surface showed slower maturation. The ISQ values in surgery were elevated (above 65), higher at necropsy and higher at 4 and 8 weeks in the SLA® group than in the other two (SLActive® ). No significant correlation was found between ISQ and BIC for each implant surface and necropsy time. Conclusion: The three surfaces analysed showed high RFA and BIC values, which were more favourable for the SLActive® surfaces. No statistical correlation was found between the RFA and BIC values in any of the three surfaces analysed. |
| وصف الملف: | application/pdf |
| تدمد: | 1422-0067 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b59c64dce9b0cf1aaf155742bfb3c84 https://pubmed.ncbi.nlm.nih.gov/31075984 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7b59c64dce9b0cf1aaf155742bfb3c84 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14220067 |
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