Impact of cumulative risk factors for expanded criteria donors on early survival after liver transplantation

التفاصيل البيبلوغرافية
العنوان: Impact of cumulative risk factors for expanded criteria donors on early survival after liver transplantation
المؤلفون: M.B. Rezende, M.P.V.C. Zurstrassen, B.H. Ferraz-Neto, S.P. Meira-Filho, R. Hidalgo, Angela Tavares Paes, F.L. Pandullo, L.E.P. Fonseca, R.C. Afonso
المصدر: Transplantation proceedings. 40(3)
سنة النشر: 2008
مصطلحات موضوعية: Adult, medicine.medical_specialty, medicine.medical_treatment, Serum sodium level, Liver transplantation, Cold Ischemia Time, law.invention, law, Risk Factors, Epidemiology, medicine, Humans, Risk factor, Retrospective Studies, Transplantation, business.industry, Patient Selection, Length of Stay, Middle Aged, Intensive care unit, Survival Analysis, Surgery, Liver Transplantation, Cumulative risk, Intensive Care Units, Regression Analysis, business, Body mass index
الوصف: There are various options to help overcome the organ shortage, including performing transplants using grafts from marginal donors with characteristics previously described as unacceptable because of the high risk of graft failure. Nowadays, expanded criteria donors for liver transplantation (OLT) is a strategy used routinely by many teams. Some donor features have been suggested to jeopardize initial function or survival; when these features are aggregated, they may impact prognosis. The aim of this study was to evaluate the impact of donor risk factors on early patient survival and retransplantation. Donor risk factors were considered to be older than 60 years, body mass index > 30, serum sodium level > 155 mEq/L, cold ischemia time > 12 hours, and intensive care unit stay > 4 days. We prospectively recorded data from 139 patients who underwent 152 OLT from March 2003 to May 2007. Patients were classified into four groups: I, no risk factors; II, one risk factor; III, two risk factors; IV, three or more risk factors. Retransplantation or OLT due to acute liver failure was considered to be an exclusion criterion. Early overall survival rate was 83.76%; 12 retransplantations were required (10.25%). Comparing the four groups, patient survivals (P = .41) and retransplantation rates (P = .518) were similar. In conclusion, cumulative risk factors showed no impact on early (30-day) recipient survival and or on the necessity of retransplantation after OLT.
تدمد: 0041-1345
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c29c19310821b46cd2b0feb6932956c
https://pubmed.ncbi.nlm.nih.gov/18455021
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....7c29c19310821b46cd2b0feb6932956c
قاعدة البيانات: OpenAIRE