COVID-19 pneumonia: computer-aided quantification of healthy lung parenchyma, emphysema, ground glass and consolidation on chest computed tomography (CT)
| العنوان: | COVID-19 pneumonia: computer-aided quantification of healthy lung parenchyma, emphysema, ground glass and consolidation on chest computed tomography (CT) |
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| المؤلفون: | Palmino Sacco, Salvatore Cappabianca, Roberta Fusco, Gianluigi Patelli, Beatrice Feragalli, Maria Antonietta Mazzei, Vincenza Granata, Antonella Petrillo, Alfonso Reginelli, Alessandro Montanelli, Fabrizio Urraro, Giuliana Giacobbe, Maria Paola Belfiore, Roberto Grassi |
| المساهمون: | Grassi, R., Belfiore, M. P., Montanelli, A., Patelli, G., Urraro, F., Giacobbe, G., Fusco, R., Granata, V., Petrillo, A., Sacco, P., Mazzei, M. A., Feragalli, B., Reginelli, A., Cappabianca, S. |
| المصدر: | La Radiologia Medica La radiologia medica |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, Computer tool, Chest Radiology, X-ray computed, Ground-glass opacity, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Parenchyma, medicine, Humans, Radiology, Nuclear Medicine and imaging, Lung, Tomography, Aged, Volume quantification, Neuroradiology, Aged, 80 and over, SARS-CoV-2, business.industry, Ultrasound, COVID-19, General Medicine, Middle Aged, medicine.disease, Pneumonia, medicine.anatomical_structure, Pulmonary Emphysema, Radiology Nuclear Medicine and imaging, COVID-19 Nucleic Acid Testing, 030220 oncology & carcinogenesis, Viral pneumonia, Radiographic Image Interpretation, Computer-Assisted, Female, medicine.symptom, Tomography, X-Ray Computed, business, Nuclear medicine, Software |
| الوصف: | Objective: To calculate by means of a computer-aided tool the volumes of healthy residual lung parenchyma, of emphysema, of ground glass opacity (GGO) and of consolidation on chest computed tomography (CT) in patients with suspected viral pneumonia by COVID-19. Materials and methods: This study included 116 patients that for suspected COVID-19 infection were subjected to the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test. A computer-aided tool was used to calculate on chest CT images healthy residual lung parenchyma, emphysema, GGO and consolidation volumes for both right and left lung. Expert radiologists, in consensus, assessed the CT images using a structured report and attributed a radiological severity score at the disease pulmonary involvement using a scale of five levels. Nonparametric test was performed to assess differences statistically significant among groups. Results: GGO was the most represented feature in suspected CT by COVID-19 infection; it is present in 102/109 (93.6%) patients with a volume percentage value of 19.50% and a median value of 0.64 L, while the emphysema and consolidation volumes were low (0.01 L and 0.03 L, respectively). Among quantified volume, only GGO volume had a difference statistically significant between the group of patients with suspected versus non-suspected CT for COVID-19 (p < < 0.01). There were differences statistically significant among the groups based on radiological severity score in terms of healthy residual parenchyma volume, of GGO volume and of consolidations volume (p < < 0.001). Conclusion: We demonstrated that, using a computer-aided tool, the COVID-19 pneumonia was mirrored with a percentage median value of GGO of 19.50% and that only GGO volume had a difference significant between the patients with suspected or non-suspected CT for COVID-19 infection. |
| تدمد: | 1826-6983 0033-8362 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed629d265861d3fc8fb0fcd478630b1 https://doi.org/10.1007/s11547-020-01305-9 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7ed629d265861d3fc8fb0fcd478630b1 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 18266983 00338362 |
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