Risk factors related to oral candidiasis in patients with primary Sjögren’s syndrome
| العنوان: | Risk factors related to oral candidiasis in patients with primary Sjögren’s syndrome |
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| المؤلفون: | Lucía Ramírez, Mariano Sanz, Gonzalo Hernández, Julia Serrano, Rosa María López‐Pintor, Mónica Fernández‐Castro, Peiteado D, S. Melchor |
| المصدر: | Medicina Oral, Patología Oral y Cirugía Bucal Serrano, Julia ; López-Pintor Muñoz, Rosa Mª ; Ramírez Martínez Acitores, Lucía ; Fernández Castro, Mónica ; Sanz Alonso, Mariano ; Melchor, Sheila ; Peiteado López, Diana ; Hernández Vallejo, Gonzalo. Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 5 2020: 12 RODERIC: Repositorio Institucional de la Universitat de Valéncia Universitat de València RODERIC. Repositorio Institucional de la Universitat de Valéncia instname |
| بيانات النشر: | Medicina Oral S.L., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Saliva, Cross-sectional study, medicine.medical_treatment, Population, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Candidiasis, Oral, Risk Factors, Internal medicine, medicine, Humans, In patient, Candida albicans, education, General Dentistry, Stomatitis, Aged, education.field_of_study, Oral Medicine and Pathology, biology, business.industry, Research, 030206 dentistry, Angular cheilitis, Middle Aged, biology.organism_classification, medicine.disease, CIENCIAS MÉDICAS [UNESCO], stomatognathic diseases, Cross-Sectional Studies, Sjogren's Syndrome, Otorhinolaryngology, UNESCO::CIENCIAS MÉDICAS, Surgery, Female, Dentures, business |
| الوصف: | Background Candidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren’s syndrome (pSS) and to study the possible factors associated with this infection. Material and Methods An observational cross-sectional study was conducted in 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) where patient based information (demographic and medical, tobacco and alcohol consumption history), intraoral parameters (presence of dentures, clinical signs of candidiasis), salivary analytical information (number of Candida albicans as colony-forming units per millilitre (CFU/mL), salivary pH levels, unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected. Results 13.1% of pSS patients presented oral signs of candidiasis. Denture stomatitis and angular cheilitis were the most common lesions. 87.5% of patients with clinical candidiasis presented reduced pH levels and salivary flow in both UWS and SWS. A significant statistical negative correlation was found between CFU/mL of Candida albicans and levels of UWS and SWS. A negative correlation was found between pH levels and CFU/mL, although not statistically significant. Conclusions A reduced salivary flow may predispose pSS patients to Candida albicans overgrowth, which may show with clinical signs. Preventive measures are of great importance to avoid and to treat this condition promptly. Key words:Sjögren’s syndrome, oral candidiasis, oral lesions, Candida albicans, oral yeast, salivary flow rate, hyposalivation. |
| اللغة: | English |
| تدمد: | 1698-6946 1698-4447 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2939b88e62637114017e347a0b24cb http://europepmc.org/articles/PMC7473438 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7f2939b88e62637114017e347a0b24cb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16986946 16984447 |
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