Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases
| العنوان: | Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases |
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| المؤلفون: | Ana M. Burga, Oluwole Fadare, Ruth A. Lininger, Fattaneh A. Tavassoli |
| المصدر: | Virchows Archiv Virchows Archiv : an international journal of pathology, vol 449, iss 5 |
| بيانات النشر: | Springer Science and Business Media LLC, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Adult, Male, Oncology, medicine.medical_specialty, Pathology, Adolescent, Clinical Sciences, Papillary, Mammary gland, Breast Neoplasms, and over, carcinoma, Breast Neoplasms, Male, Pathology and Forensic Medicine, Metastasis, Breast cancer, papillary, Internal medicine, 80 and over, medicine, Carcinoma, cancer, Humans, Mucinous carcinoma, Neoplasm Invasiveness, Breast, Neoplasm Metastasis, Child, skin and connective tissue diseases, Molecular Biology, breast, Aged, Cancer, Aged, 80 and over, business.industry, Cell Biology, General Medicine, Middle Aged, medicine.disease, medicine.anatomical_structure, Cutaneous melanoma, Original Article, Breast carcinoma, business |
| الوصف: | The current investigation was conducted to evaluate the proportional distribution of the various histologic subtypes (including newly recognized variants) of male breast carcinomas, to determine whether any histologic subtypes occur with a frequency that is markedly discordant with the expected frequencies from published data on parallel female breast tumors. We also aimed to document the distribution of malignancies metastatic to the breast. Seven hundred fifty-nine archived cases of primary invasive carcinoma involving the male breast were retrieved and sub-categorized into histologic subtypes according to contemporary criteria. Six hundred forty-three (84.7%) tumors were pure infiltrating ductal carcinoma (IDC) not otherwise specified. The most common of the remainder included papillary carcinoma with invasion in the form of IDC (n = 34), mixed IDC and mucinous carcinoma (n = 26), and pure mucinous carcinoma (n = 21). In 19 cases, metastases from other sites involved the breast, most commonly (58%) cutaneous melanoma. Invasive carcinoma of the male breast appears to display a morphologic spectrum and distribution of histologic subtypes that is comparable to those of the female breast, with some expected variation. Compared with published experience on their female counterparts, there is a two-fold increase in the frequency of invasive papillary carcinoma in the male breast. Finally, the most common tumor metastatic to the male breast in this series was cutaneous melanoma. |
| وصف الملف: | application/pdf |
| تدمد: | 1432-2307 0945-6317 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f33df2d4a74d9582b2b1339487529a9 https://doi.org/10.1007/s00428-006-0305-3 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7f33df2d4a74d9582b2b1339487529a9 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14322307 09456317 |
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