Viral infection in thymoma and thymic tumors with autoimmune diseases
| العنوان: | Viral infection in thymoma and thymic tumors with autoimmune diseases |
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| المؤلفون: | Shicong Li, Rui Chang, Shuning Duan, Peng Zhang |
| المصدر: | Thoracic Cancer Thoracic Cancer, Vol 12, Iss 22, Pp 2971-2980 (2021) |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Thymoma, Thymic Tumors, chemical and pharmacologic phenomena, Review, virus, Opportunistic Infections, Viral infection, Virus, Pathogenesis, Immune system, Immunity, hemic and lymphatic diseases, medicine, Humans, autoimmune diseases, neoplasms, RC254-282, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, General Medicine, Thymus Neoplasms, medicine.disease, infection, surgical procedures, operative, Oncology, Virus Diseases, Immunology, Etiology, business |
| الوصف: | A thymoma is a type of thymic tumor which is rarely malignant that is frequently reported in adult patients. A number of thymoma‐related immune disorders are observed including autoimmune diseases, which suggests a strong connection between thymoma development and immunological mechanisms. Characterized by association with humoral and cellular immunodeficiency, thymoma patients are susceptible to opportunistic infections by environmental factors. Recent reports have suggested that viral infection may play a role in the etiological mechanisms of thymoma development associated with dysregulated immunity. In this review, we summarize the case reports and studies related to viral infection, such as CMV, EBV and HSV, that probably play a part in the pathogenesis of thymoma and related diseases. Furthermore, we demonstrate the underlying mechanisms by which viruses may induce the occurrence of thymoma with autoimmune diseases. Lastly, we discuss the potential application of antiviral therapy in the treatment of thymic diseases. |
| تدمد: | 1759-7714 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f75208e7ee734bdf35fbdac42c18912 https://pubmed.ncbi.nlm.nih.gov/34532982 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....7f75208e7ee734bdf35fbdac42c18912 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17597714 |
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