Prognostic value of cognitive functioning for global functional recovery in first-episode schizophrenia
| العنوان: | Prognostic value of cognitive functioning for global functional recovery in first-episode schizophrenia |
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| المؤلفون: | Obdulia Martínez-García, Rocío Pérez-Iglesias, José Manuel Rodríguez-Sánchez, Benedicto Crespo-Facorro, Gema Pardo-García, J. L. Vázquez-Barquero, César González-Blanch |
| المصدر: | Psychological Medicine. 40:935-944 |
| بيانات النشر: | Cambridge University Press (CUP), 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Neuropsychological Tests, Logistic regression, Cohort Studies, Disability Evaluation, Young Adult, medicine, Humans, Attention, Longitudinal Studies, Psychiatry, Applied Psychology, Randomized Controlled Trials as Topic, Psychiatric Status Rating Scales, First episode, Rehabilitation, business.industry, Neuropsychology, Rehabilitation, Vocational, Cognition, Prognosis, medicine.disease, Psychiatry and Mental health, Psychotic Disorders, Spain, Cognitive remediation therapy, Schizophrenia, Female, Schizophrenic Psychology, Independent Living, Cognition Disorders, business, Social Adjustment, Antipsychotic Agents, Cohort study, Clinical psychology |
| الوصف: | BackgroundIt has become widely accepted that cognitive deficits in schizophrenia are related to functional outcome. However, it remains to be seen whether these associations are relevant for predicting which cases will have a global functional recovery. In this study, we attempt to determine whether global functional recovery (integrating social and occupational outcomes) after first-episode schizophrenia (FES) can be predicted by cognitive variables.MethodA total of 131 FES patients with functional deficits (n=97) and functional recovery (n=34) as determined at 1-year follow-up were examined. Neuropsychological, sociodemographic, pre-morbid and clinical data at baseline were analysed using independent groups comparisons and a logistic regression method.ResultsSustained attention and negative symptoms emerged as significant predictors of good global functional outcome. Although the model revealed a high accuracy (91%) in the classification of patients with functional deficits, it was unacceptably low (26%) in the classification of patients with global functional recovery.ConclusionsThe limitations found in the prediction of a favourable global functional outcome may well be an indication for a need to address the role of other factors not commonly included in longitudinal studies of long-term outcomes in schizophrenia. |
| تدمد: | 1469-8978 0033-2917 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8133301664df2c59af211dbb991d07d1 https://doi.org/10.1017/s0033291709991267 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8133301664df2c59af211dbb991d07d1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14698978 00332917 |
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