Patterns of Coagulopathy during Liver Transplantation: Experience with the First 75 Cases using Thrombelastography
| العنوان: | Patterns of Coagulopathy during Liver Transplantation: Experience with the First 75 Cases using Thrombelastography |
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| المؤلفون: | Robert M Jones, Greg Przybylowski, G Liu, Peter R McCall, Peter W Angus, P L McNicol, I D Harley, J Bowkett, Kenneth J. Hardy |
| المصدر: | Anaesthesia and Intensive Care. 22:659-665 |
| بيانات النشر: | SAGE Publications, 1994. |
| سنة النشر: | 1994 |
| مصطلحات موضوعية: | medicine.medical_specialty, medicine.medical_treatment, Blood Loss, Surgical, Blood Component Transfusion, 030204 cardiovascular system & hematology, Liver transplantation, Critical Care and Intensive Care Medicine, Fibrin Fibrinogen Degradation Products, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Monitoring, Intraoperative, Coagulopathy, medicine, Humans, Blood Coagulation, medicine.diagnostic_test, Platelet Count, business.industry, Fibrinolysis, Fibrinogen, Transfusion Reaction, 030208 emergency & critical care medicine, Blood Coagulation Disorders, medicine.disease, Thromboelastography, Liver Transplantation, Thrombelastography, Surgery, Transplantation, Anesthesiology and Pain Medicine, Anesthesia, Reperfusion, Partial Thromboplastin Time, Prothrombin, Serum Globulins, business, Liver function tests, Partial thromboplastin time |
| الوصف: | Using both conventional laboratory clotting profile and thrombelastography, coagulation status was monitored intraoperatively during liver transplantation in the first 75 cases performed at the Austin Hospital between June 1988 and October 1992. Superimposed on a baseline coagulopathy due to liver disease is a specific pattern of coagulation disturbance which occurs during a liver transplant. Fibrinolysis occurs in the anhepatic stage, worsens with early reperfusion and then spontaneously resolves. In addition reperfusion is associated with a transient clotting defect. If blood loss is excessive, coagulopathy due to massive transfusion may compound the situation. Thrombelastography is a measurement technique allowing rapid on-site assessment of functional clotting status’. It is particularly useful in liver transplant surgery. In combination with clinical bleeding assessment it facilitates selective use of component therapy (fresh frozen plasma, platelets and cryoprecipitate) and specific drug treatment only when it is appropriate. It also acts as a liver function test, being especially useful in assessing the graft after reperfusion. |
| تدمد: | 1448-0271 0310-057X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824463727969805b60f307c6f9c7aa98 https://doi.org/10.1177/0310057x9402200603 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....824463727969805b60f307c6f9c7aa98 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14480271 0310057X |
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