Vitamin D deficiency in solid‐organ transplant recipients from a Spanish Mediterranean population
| العنوان: | Vitamin D deficiency in solid‐organ transplant recipients from a Spanish Mediterranean population |
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| المؤلفون: | C. Berastegui, I. B. Torres, C. Juárez‐Dobjanschi, Carla Ferrándiz-Pulido, Vicente García-Patos, L. Castells, I. Zarzoso‐Muñoz, F. Moreso |
| المصدر: | Clinical and Experimental Dermatology. 44:e103-e109 |
| بيانات النشر: | Oxford University Press (OUP), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Vitamin, medicine.medical_specialty, Population, Transplants, Dermatology, Logistic regression, Gastroenterology, vitamin D deficiency, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Internal medicine, Vitamin D and neurology, Humans, Medicine, Vitamin D, education, Aged, Calcifediol, education.field_of_study, Mediterranean Region, business.industry, Middle Aged, Vitamin D Deficiency, medicine.disease, Transplant Recipients, Cross-Sectional Studies, chemistry, Spain, 030220 oncology & carcinogenesis, Cohort, Sunlight, Female, Seasons, Skin cancer, business, Blood sampling |
| الوصف: | BACKGROUND Solid-organ transplant recipients (SOTRs) are at risk of developing vitamin D deficiency, mainly caused by reduced sunlight exposure with subsequent low vitamin D synthesis in the skin. AIM To analyse whether SOTRs from a Spanish Mediterranean region were vitamin D-deficient. METHODS This was a cross-sectional, descriptive and observational study in a transplantation-specialized Dermatological Unit from a Mediterranean area to determine the calcidiol levels of a cohort of 78 consecutively attending patients not receiving vitamin D supplements. Serum 25(OH)D3 levels were determined and clinical characteristics were collected. Logistic regression analysis was used to analyse variables associated with dichotomized 25(OH)D3 levels (≤ or > 10 ng/mL). RESULTS The cohort comprised 30 lung, 29 kidney and 19 liver transplant recipients. Mean calcidiol was 18 ± 9 ng/mL. Deficiency of 25(OH)D3 was present in 19% of patients, while 68% had insufficient levels and 13% had sufficient levels. Following multivariate logistic regression analysis, the season of blood sampling remained the only predictor of deficient 25(OH)D3 levels. CONCLUSION Despite living in a mid-latitude country with sunny weather, our SOTR population was at high risk of developing hypovitaminosis D, especially in autumn/winter. Avoiding sun exposure is important to prevent skin cancer, but careful monitoring of vitamin D status is recommended, with supplementation if hypovitaminosis D is detected. |
| تدمد: | 1365-2230 0307-6938 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cfe0b6304400eacb805214112fdf0c https://doi.org/10.1111/ced.13915 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....82cfe0b6304400eacb805214112fdf0c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652230 03076938 |
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