Cascade Benzannulation Approach for the Syntheses of Lipocarbazoles, Carbazomycins, and Related Alkaloids
| العنوان: | Cascade Benzannulation Approach for the Syntheses of Lipocarbazoles, Carbazomycins, and Related Alkaloids |
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| المؤلفون: | Shuvendu Saha, Modhu Sudan Maji, Ankush Banerjee |
| المصدر: | The Journal of Organic Chemistry. 87:4343-4359 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Alkaloids, Organic Chemistry, Carbazoles, Indole Alkaloids |
| الوصف: | Herein, a state-of-the-art one-pot cascade benzannulation technique for the efficacious synthesis of valuable 3-hydroxy-2-methyl carbazoles, a linchpin of more than 25 carbazole-based alkaloids, is unveiled from readily affordable fundamental commodities. The key step of this strategy is gaining aromaticity by site-selective elimination of hydroxyl group controlled by nucleophilicity of the indole ring. The present strategy shows excellent functional group tolerance with a broad substrate scope. The utility of this convenient approach was appealingly exemplified |
| تدمد: | 1520-6904 0022-3263 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fe8b43d7f751cf1dc814b9047cbf92 https://doi.org/10.1021/acs.joc.2c00042 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....82fe8b43d7f751cf1dc814b9047cbf92 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15206904 00223263 |
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