Comparison of Assist/Control Ventilation with and without Volume Guarantee in Term or Near-Term Infants
| العنوان: | Comparison of Assist/Control Ventilation with and without Volume Guarantee in Term or Near-Term Infants |
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| المؤلفون: | Handan Bezirganoglu, Nilufer Okur, Mehmet Buyuktiryaki, Serife S. Oguz, Evrim A. Dizdar, Fatma N. Sari |
| المصدر: | American Journal of Perinatology. |
| بيانات النشر: | Georg Thieme Verlag KG, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology |
| الوصف: | Objectives This study aimed to compare the effects of volume guarantee (VG) combined with assist/control (AC) ventilation to AC alone on hypocarbia episodes and extubation success in infants born at or near term. Methods In this prospective cohort study, infants >34 weeks of gestation at birth, who were born in our hospital supported by synchronized, time-cycled, pressure limited, assist/control ventilation (AC) or assist-controlled VG mechanical ventilation (AC + VG) were included. After admission, infants received either AC or VG + AC using by Leoni Plus ventilator. The ventilation mode was left to the clinician. In the AC group, peak airway pressure was set clinically. In the VG + AC group, desired tidal volume was set at 5 mL/kg, with the ventilator adjusting peak inspiratory pressure to deliver this volume. The study was completed once the patient extubated. Results There were 35 patients in each group. Incidence of hypocarbia was lower in the VG + AC compared with AC (%17.1 and 22.8%, respectively) but statistically not significant. Out-of-range partial pressure of carbon dioxide (PCO2) levels were lower in the VG + AC group and it reached borderline statistical significance (p = 0.06). The median extubation time was 70 (42–110) hours in the VG + AC group, 89.5 (48.5–115.5) hours in the AC group, and it did not differ between groups (p = 0.47). Conclusion We found combining AC and VG ventilation compared with AC ventilation alone yielded similar hypocarbia episodes and extubation time for infants of >34 gestational weeks with borderline significance lower out-of-range PCO2 incidence. Key Points |
| تدمد: | 1098-8785 0735-1631 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bebeff6f913ef9c8f3c75958636030 https://doi.org/10.1055/a-1862-0078 |
| رقم الأكسشن: | edsair.doi.dedup.....83bebeff6f913ef9c8f3c75958636030 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10988785 07351631 |
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