Transient Diabetes Insipidus Following Organophosphorus Poisoning
| العنوان: | Transient Diabetes Insipidus Following Organophosphorus Poisoning |
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| المؤلفون: | Amid Bhujel, Niraj Kumar Keyal |
| المصدر: | The Journal of Critical Care Medicine The Journal of Critical Care Medicine, Vol 5, Iss 4, Pp 145-148 (2019) |
| بيانات النشر: | Sciendo, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | desmopressin, endocrine system diseases, 030209 endocrinology & metabolism, Case Report, urologic and male genital diseases, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, medicine, 030212 general & internal medicine, Desmopressin, Urine specific gravity, business.industry, RC86-88.9, digestive, oral, and skin physiology, Glasgow Coma Scale, Medical emergencies. Critical care. Intensive care. First aid, organophosphorus, General Medicine, medicine.disease, Intensive care unit, female genital diseases and pregnancy complications, urine, Blood pressure, diabetes insipidus, Anesthesia, Diabetes insipidus, business, Complication, hormones, hormone substitutes, and hormone antagonists, Low sodium, medicine.drug |
| الوصف: | Introduction Organophosphorus poisoning is the most common poison used for suicidal attempt in Nepal. Diabetes insipidus is unusual and rare in this poisoning. This is the second case report of Diabetes insipidus developing in organophosphorus poisoning. Management of diabetes insipidus includes desmopressin and adequate fluid management. Case presentation A 34-year-old female patient accompanied by her father presented at the Emergency department with an alleged history of ingestion of unknown amount of chlorpyrifos, cypermethrin and quinalphos. On admission, she had a Glasgow Coma Scale (GCS) of 7/15. Her blood pressure was 110/60 mm Hg, pulse 54/min, respiratory rate 45/min and saturation 35% on room air, pinpoint pupil reactive to light and bilateral crepitations. She was immediately resuscitated with two litres of normal saline and intubated with a 7 mm endotracheal tube. Atropinisation was done, and pralidoxime was started. She developed a urine output of 250-350 ml per hour with rising sodium and serum osmolality. The urine examination showed low sodium and urine specific gravity. A diagnosis of diabetes insipidus was made. There was no immediate improvement in her GCS. She was managed with 5% dextrose and subcutaneous desmopressin and was transferred out of the intensive care unit on the sixth day and was discharged from hospital on the fifteenth day. Conclusion Diabetes insipidus is a rare transient complication in organophosphorus poisoning that requires careful observation and early management with desmopressin and adequate fluid balance to improve patient outcome. |
| اللغة: | English |
| تدمد: | 2393-1817 2393-1809 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841424e1bb089ccceb138b582dd2e664 http://europepmc.org/articles/PMC6942452 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....841424e1bb089ccceb138b582dd2e664 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23931817 23931809 |
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