The 5-HTTLPR polymorphism impacts moral permissibility of impersonal harmful behaviors
| العنوان: | The 5-HTTLPR polymorphism impacts moral permissibility of impersonal harmful behaviors |
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| المؤلفون: | Xiaocai Gao, Linlin He, Yafang Yang, Mengying Xue, Rongjun Yu, Wenxuan Guo, Mengfei Zhang, Chunlan Wang, Xiaohan Li, Pingyuan Gong |
| المصدر: | Social Cognitive and Affective Neuroscience |
| بيانات النشر: | Oxford University Press, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Serotonin, impersonal harm, Synaptic cleft, Genotype, Cognitive Neuroscience, Emotions, Experimental and Cognitive Psychology, Original Manuscript, Morals, 050105 experimental psychology, personal harm, serotonin transporter gene, Developmental psychology, cross-sectional analysis, 03 medical and health sciences, Judgment, 0302 clinical medicine, two-wave comparison, Humans, 0501 psychology and cognitive sciences, Serotonin transporter, Alleles, Serotonin Plasma Membrane Transport Proteins, Polymorphism, Genetic, biology, 05 social sciences, General Medicine, moral judgment, 5 httlpr polymorphism, Cross-Sectional Studies, Cohort, biology.protein, Female, Psychology, 030217 neurology & neurosurgery |
| الوصف: | Inspired by the roles of serotonin in an emotional aversion to harmful actions, we examined to what extent serotonin transporter gene (5-HTT)–linked polymorphic region (5-HTTLPR), a proxy for measuring serotonin function, underpinned the individual differences in moral judgment through cross-sectional analysis and two-wave comparison. The cross-sectional analysis with a larger cohort (N = 1197) showed that the SS carriers of the 5-HTTLPR polymorphism, corresponding to the low ratio of serotonin recycling from the synaptic cleft, rated impersonal harmful actions (e.g. flipping a switch to divert a train to hit one person instead of five people) as more permissible as compared with the L-allele carriers. The two-wave comparison with a subsample from the larger cohort (N = 563) indicated that the association between 5-HTTLPR polymorphism and moral permissibility of impersonal harmful actions was stable from wave 1 to wave 2. Thus, these findings highlight the importance of the 5-HTTLPR polymorphism to harmful moral behaviors. |
| اللغة: | English |
| تدمد: | 1749-5024 1749-5016 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84360da36132e0d4ca74fa9bcc3e4bd2 http://europepmc.org/articles/PMC6847979 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....84360da36132e0d4ca74fa9bcc3e4bd2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17495024 17495016 |
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