Authorization Patterns, Safety, and Effectiveness of Medical Cannabis in Quebec
| العنوان: | Authorization Patterns, Safety, and Effectiveness of Medical Cannabis in Quebec |
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| المؤلفون: | Maja Kalaba, Cynthia El Hage, Laura MacNair, Mark A. Ware, Graham M L Eglit, Lucile Rapin, Erin Prosk, Erica N. Peters |
| المصدر: | Cannabis and Cannabinoid Research |
| بيانات النشر: | Mary Ann Liebert, Inc., publishers, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | safety, Adult, medicine.medical_specialty, medicine.medical_treatment, Medical Marijuana, Medicine, Cannabidiol, Humans, Pharmacology (medical), Dronabinol, Psychiatry, Tetrahydrocannabinol, Original Research, Cannabis, Pharmacology, real-world data, business.industry, symptom improvement, Authorization, Quebec, medical cannabis, Middle Aged, clinical practice, Complementary and alternative medicine, Symptom improvement, Medical cannabis, Anxiety, Observational study, Female, Cannabinoid, medicine.symptom, business, medicine.drug |
| الوصف: | Introduction: Despite increasing demand for data, little is known about the authorization patterns, safety, and effectiveness of medical cannabis products. Materials and Methods: We conducted a 2 year observational study of adult patients who were legally authorized a medical cannabis product from a single licensed producer; we captured and analyzed authorized cannabis use patterns by cannabinoid profile (tetrahydrocannabinol [THC]-dominant; cannabidiol [CBD]-dominant; and balanced (THC:CBD) and clinical outcomes using standardized outcome measures every 3 months for 12 months at a network of medical cannabis clinics in Quebec, Canada. Results: We recruited 585 patients (average age 56.5 years), of whom 61% identified as female and 85% reported pain as their primary complaint. Over 12 months, there was a significant increase in the number of products authorized (Z=2.59, p=0.01). The proportion of authorizations for a THC-dominant or CBD-dominant product increased relative to the proportion of authorizations for a balanced (THC:CBD) product (all p |
| اللغة: | English |
| تدمد: | 2378-8763 2578-5125 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cc2e25af396d0f8a8ac6933e42676c http://europepmc.org/articles/PMC8713264 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....86cc2e25af396d0f8a8ac6933e42676c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23788763 25785125 |
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