Anti-myelin oligodendrocyte glycoprotein antibodies: Magnetic resonance imaging findings in a case series and a literature review
| العنوان: | Anti-myelin oligodendrocyte glycoprotein antibodies: Magnetic resonance imaging findings in a case series and a literature review |
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| المؤلفون: | Michaela Cellina, Giancarlo Oliva, Matteo Ciocca, Vincenza Fetoni, Marta Pirovano |
| المصدر: | The Neuroradiology Journal. 31:69-82 |
| بيانات النشر: | SAGE Publications, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Male, 0301 basic medicine, Neuroimaging of Neurological Disorders, Multiple Sclerosis, Optic Neuritis, Central nervous system, Contrast Media, Enzyme-Linked Immunosorbent Assay, Myelin oligodendrocyte glycoprotein, 03 medical and health sciences, Myelin, 0302 clinical medicine, Recurrence, Organometallic Compounds, medicine, Humans, Radiology, Nuclear Medicine and imaging, Optic neuritis, Autoantibodies, Retrospective Studies, Neuromyelitis optica, biology, medicine.diagnostic_test, business.industry, Multiple sclerosis, Neuromyelitis Optica, Autoantibody, Magnetic resonance imaging, General Medicine, medicine.disease, Magnetic Resonance Imaging, 030104 developmental biology, medicine.anatomical_structure, Immunology, biology.protein, Female, Myelin-Oligodendrocyte Glycoprotein, Neurology (clinical), Tomography, X-Ray Computed, business, 030217 neurology & neurosurgery |
| الوصف: | Myelin oligodendrocyte glycoprotein is a protein exclusively expressed on the surface of oligodendrocytes and myelin in the central nervous system. Antibodies against myelin oligodendrocyte glycoprotein were initially detected in children with demyelinating syndromes, and more recently reported in a broad spectrum of central nervous system demyelinating diseases in adults, including neuromyelitis optica spectrum disorders and bilateral optic neuritis. Patients with myelin oligodendrocyte glycoprotein antibody-associated demyelination appear to have unique clinical and radiological features. To the best of our knowledge a series of Italian patients with optic neuritis and positivity to myelin oligodendrocyte glycoprotein antibodies has not yet been reported and the paper on myelin oligodendrocyte glycoprotein antibodies are more focused on clinical features, diagnosis and outcome than on the radiological appearance, so we want to retrospectively report magnetic resonance imaging features of a group of eight patients, who came to our Ophthalmologic Emergency Department for optic neuritis and were found seropositive for myelin oligodendrocyte glycoprotein antibodies, comparing our data with the findings described in the literature. |
| تدمد: | 2385-1996 1971-4009 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86deaf5a555d50af0c57039e373dbad6 https://doi.org/10.1177/1971400917698856 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....86deaf5a555d50af0c57039e373dbad6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23851996 19714009 |
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