Mesenchymal Stem Cells for Mitigating Radiotherapy Side Effects
| العنوان: | Mesenchymal Stem Cells for Mitigating Radiotherapy Side Effects |
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| المؤلفون: | Lan Luo, Ai-Bin Tao, Ting Lan, Wen-Wen Cui, Xu Yang, Kai-Xuan Wang, Tao-Sheng Li |
| المصدر: | Cells, Vol 10, Iss 294, p 294 (2021) Cells |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | mesenchymal stem cells, Lung, business.industry, medicine.medical_treatment, Mesenchymal stem cell, Cell- and Tissue-Based Therapy, General Medicine, Review, Radiation therapy, Paracrine signalling, medicine.anatomical_structure, lcsh:Biology (General), Neoplasms, medicine, Cancer research, Humans, Secretion, Stem cell, Mesodermal Differentiation, business, Radiation Injuries, radiation-induced injury, Radiation injury, lcsh:QH301-705.5, radiotherapy |
| الوصف: | Radiation therapy for cancers also damages healthy cells and causes side effects. Depending on the dosage and exposure region, radiotherapy may induce severe and irreversible injuries to various tissues or organs, especially the skin, intestine, brain, lung, liver, and heart. Therefore, promising treatment strategies to mitigate radiation injury is in pressing need. Recently, stem cell-based therapy generates great attention in clinical care. Among these, mesenchymal stem cells are extensively applied because it is easy to access and capable of mesodermal differentiation, immunomodulation, and paracrine secretion. Here, we summarize the current attempts and discuss the future perspectives about mesenchymal stem cells (MSCs) for mitigating radiotherapy side effects. |
| اللغة: | English |
| تدمد: | 2073-4409 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8885e4d1afc26e817b1b5c5406a83da8 https://www.mdpi.com/2073-4409/10/2/294 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8885e4d1afc26e817b1b5c5406a83da8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20734409 |
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