Leveraging European infrastructures to access 1 million human genomes by 2022
| العنوان: | Leveraging European infrastructures to access 1 million human genomes by 2022 |
|---|---|
| المؤلفون: | David Salgado, Helen Parkinson, Jaap Heringa, Ivo Gut, Gert Matthijs, Paul Flicek, Ewan Birney, Peter Goodhand, Andres Metspalu, Ilkka Lappalainen, Aarno Palotie, Rachel Drysdale, Michael Baudis, Bengt Persson, Steven Newhouse, Serena Scollen, Jan O. Korbel, Regina Becker, Nick Juty, Angela Page, Jef Hooyberghs, Francesco Florindi, Susheel Varma, Marc Van den Bulcke, Jordi Rambla, Alfonso Valencia, Brane Leskošek, Morris A. Swertz, Petr Holub, Thomas Keane, Salvador Capella-Gutierrez, Cath Brooksbank, Tommi Nyrönen, Niklas Blomberg, Christophe Béroud, Michaela Th. Mayrhofer, Søren Brunak, Arcadi Navarro, Gary Saunders, Erik Steinfelder, Sergi Beltran |
| المساهمون: | Computer Science, AIMMS |
| المصدر: | Saunders, G, Baudis, M, Becker, R, Beltran, S, Béroud, C, Birney, E, Brooksbank, C, Brunak, S, Van den Bulcke, M, Drysdale, R, Capella-Gutierrez, S, Flicek, P, Florindi, F, Goodhand, P, Gut, I, Heringa, J, Holub, P, Hooyberghs, J, Juty, N, Keane, T M, Korbel, J O, Lappalainen, I, Leskosek, B, Matthijs, G, Mayrhofer, M T, Metspalu, A, Navarro, A, Newhouse, S, Nyrönen, T, Page, A, Persson, B, Palotie, A, Parkinson, H, Rambla, J, Salgado, D, Steinfelder, E, Swertz, M A, Valencia, A, Varma, S, Blomberg, N & Scollen, S 2019, ' Leveraging European infrastructures to access 1 million human genomes by 2022 ', Nature Reviews Genetics, vol. 20, no. 11, pp. 693-701 . https://doi.org/10.1038/s41576-019-0156-9 Saunders, G, Baudis, M, Becker, R, Beltran, S, Béroud, C, Birney, E, Brooksbank, C, Brunak, S, Van den Bulcke, M, Drysdale, R, Capella-Gutierrez, S, Flicek, P, Florindi, F, Goodhand, P, Gut, I, Heringa, J, Holub, P, Hooyberghs, J, Juty, N, Keane, T M, Korbel, J O, Lappalainen, I, Leskosek, B, Matthijs, G, Mayrhofer, M T, Metspalu, A, Navarro, A, Newhouse, S, Nyrönen, T, Page, A, Persson, B, Palotie, A, Parkinson, H, Rambla, J, Salgado, D, Steinfelder, E, Swertz, M A, Valencia, A, Varma, S, Blomberg, N & Scollen, S 2019, ' Leveraging European infrastructures to access 1 million human genomes by 2022 ', Nature Reviews. Genetics, vol. 20, pp. 693-701 . https://doi.org/10.1038/s41576-019-0156-9 Nature Reviews Genetics, 20(11), 693-701. Nature Publishing Group Nat Rev Genet Digital.CSIC. Repositorio Institucional del CSIC instname |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Biomedical Research, Big data, Declaration, Genomics, Human genomics, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, SDG 17 - Partnerships for the Goals, SDG 3 - Good Health and Well-being, Human Genome Project, Health care, Genetics, Humans, Clinical genetics, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Genome, Human, business.industry, Precision medicine, Data science, Europe, Data sharing, Next-generation sequencing, Human genome, business, Medical genomics, 030217 neurology & neurosurgery |
| الوصف: | Human genomics is undergoing a step change from being a predominantly research-driven activity to one driven through health care as many countries in Europe now have nascent precision medicine programmes. To maximize the value of the genomic data generated, these data will need to be shared between institutions and across countries. In recognition of this challenge, 21 European countries recently signed a declaration to transnationally share data on at least 1 million human genomes by 2022. In this Roadmap, we identify the challenges of data sharing across borders and demonstrate that European research infrastructures are well-positioned to support the rapid implementation of widespread genomic data access. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1471-0056 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d6bc39bcb15c5352062675203b0cf2 https://research.vu.nl/ws/files/237461982/Leveraging_European_infrastructures_to_access_1_million_human_genomes_by_2022.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....89d6bc39bcb15c5352062675203b0cf2 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14710056 |
|---|