RESISTIN GENE POLYMORPHISM AND NONALCOHOLIC FATTY LIVER DISEASE RISK
| العنوان: | RESISTIN GENE POLYMORPHISM AND NONALCOHOLIC FATTY LIVER DISEASE RISK |
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| المؤلفون: | Seidamir Pasha TABAEIAN, Touraj MAHMOUDI, Gholamreza REZAMAND, Hossein NOBAKHT, Reza DABIRI, Hamid FARAHANI, Asadollah ASADI, Mohammad Reza ZALI |
| المصدر: | Arquivos de Gastroenterologia, Issue: ahead, Published: 14 NOV 2022 Arquivos de Gastroenterologia v.59 n.4 2022 Arquivos de gastroenterologia Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia instacron:IBEPEGE |
| بيانات النشر: | FapUNIFESP (SciELO), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | variant, DHGNA, NAFLD, Gastroenterology, Gene, RETN, resistina, resistin, variante |
| الوصف: | Background Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease and one of the main global health issues in which liver fat surpasses 5% of hepatocytes without the secondary causes of lipid accumulation or excessive alcohol consumption. Owing to the link between NAFLD and insulin resistance (IR) and obesity and the role of resistin in theses metabolic disorders, we explored the possible association between resistin gene (RETN) variant and NAFLD. Methods A total of 308 unrelated subjects, including 152 patients with biopsy-proven NAFLD and 156 controls were enrolled and genotyped for the RETN gene rs3745367 variant using PCR-RFLP method. Results NAFLD patients had higher liver enzymes, systolic blood pressure (SBP), and diastolic blood pressure (DBP) than the controls (P |
| وصف الملف: | text/html |
| تدمد: | 1678-4219 0004-2803 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a38b67666fe813b703b0d52e2ca104d https://doi.org/10.1590/s0004-2803.202204000-86 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8a38b67666fe813b703b0d52e2ca104d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16784219 00042803 |
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