Bioactive Plasma Coatings on Orthodontic Brackets: In Vitro Metal Ion Release and Cytotoxicity
| العنوان: | Bioactive Plasma Coatings on Orthodontic Brackets: In Vitro Metal Ion Release and Cytotoxicity |
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| المؤلفون: | Alex Cavallaro, Giampiero Rossi-Fedele, Craig W. Dreyer, Peter S. Zilm, Panthihage Ruvini L. Dabare, Krasimir Vasilev, Neethu Ninan, Esma J. Doğramacı, Lasni Samalka Kumarasinghe |
| المساهمون: | Kumarasinghe, Lasni Samalka, Ninan, Neethu, Dabare, Panthihage Ruvini Lakshika, Cavallaro, Alex, Doğramacı, Esma J, Rossi-Fedele, Giampiero, Dreyer, Craig, Vasilev, Krasimir, Zilm, Peter |
| المصدر: | Coatings Volume 11 Issue 7 Coatings, Vol 11, Iss 857, p 857 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Materials science, Biocompatibility, Metal ions in aqueous solution, Metal toxicity, 02 engineering and technology, Metal, 03 medical and health sciences, 0302 clinical medicine, biocompatibility, Materials Chemistry, metal ion release, Cytotoxicity, chemistry.chemical_classification, orthodontic brackets, plasma polymerisation, 030206 dentistry, Surfaces and Interfaces, Plasma, Polymer, 021001 nanoscience & nanotechnology, Engineering (General). Civil engineering (General), Surfaces, Coatings and Films, chemistry, Chemical engineering, visual_art, visual_art.visual_art_medium, TA1-2040, 0210 nano-technology, Layer (electronics), amino acid |
| الوصف: | The metal ion release characteristics and biocompatibility of meta-based materials are key factors that influence their use in orthodontics. Although stainless steel-based alloys have gained much interest and use due to their mechanical properties and cost, they are prone to localised attack after prolonged exposure to the hostile oral environment. Metal ions may induce cellular toxicity at high dosages. To circumvent these issues, orthodontic brackets were coated with a functional nano-thin layer of plasma polymer and further immobilised with enantiomers of tryptophan. Analysis of the physicochemical properties confirmed the presence of functional coatings on the surface of the brackets. The quantification of metal ion release using mass spectrometry proved that plasma functionalisation could minimise metal ion release from orthodontic brackets. Furthermore, the biocmpatibility of the brackets has been improved after functionalisation. These findings demon-strate that plasma polymer facilitated surface functionalisation of orthodontic brackets is a promising approach to reducing metal toxicity without impacting their bulk properties. Refereed/Peer-reviewed |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2079-6412 |
| DOI: | 10.3390/coatings11070857 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adaa2ad0da715f94ab80b75a8ad1ae6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....8adaa2ad0da715f94ab80b75a8ad1ae6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20796412 |
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| DOI: | 10.3390/coatings11070857 |