أعرض في EDS

Mortality prediction by acute kidney injury biomarkers in comparison with serum creatinine

التفاصيل البيبلوغرافية
العنوان: Mortality prediction by acute kidney injury biomarkers in comparison with serum creatinine
المؤلفون: Kengo Mayumi, Naoki Yahagi, Kent Doi, Toshifumi Asada, Ryota Inokuchi, Takehiro Matsubara, Rei Isshiki, Maki Sumida, Masaomi Nangaku, Takahiro Hiruma, Takeshi Ishii, Miyuki Yamamoto, Eisei Noiri
المصدر: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 19(8)
سنة النشر: 2014
مصطلحات موضوعية: Male, medicine.medical_specialty, Health, Toxicology and Mutagenesis, Urinary system, Clinical Biochemistry, urologic and male genital diseases, Biochemistry, Gastroenterology, Cohort Studies, chemistry.chemical_compound, Internal medicine, medicine, Humans, Mortality prediction, Intensive care medicine, Aged, Creatinine, urogenital system, business.industry, Acute kidney injury, Acute Kidney Injury, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, Derivation cohort, chemistry, N acetyl β d glucosaminidase, Female, business, Validation cohort, Biomarkers
الوصف: Objectives: To investigate the performance of acute kidney injury (AKI) biomarkers for mortality prediction.Materials and methods: Cutoff values of urinary L-type fatty acid-binding protein (L-FABP) and N-acetyl-β-d-glucosaminidase (NAG) for AKI diagnosis in ICU were determined in the derivation cohort. The performance of these AKI biomarkers for mortality prediction was evaluated in the validation cohort with stratification of serum-creatinine based AKI diagnosis.Results: Mortality in the AKI patients diagnosed by serum creatinine was increased remarkably when urinary L-FABP and NAG were positive.Conclusions: These AKI biomarkers can specifically detect high-risk patients among creatinine-base diagnosed AKI.
تدمد: 1366-5804
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc07f957069d4d2dc0c21f52a613a07
https://pubmed.ncbi.nlm.nih.gov/25271041
رقم الأكسشن: edsair.doi.dedup.....8bc07f957069d4d2dc0c21f52a613a07
قاعدة البيانات: OpenAIRE
الوصف
تدمد:13665804