Microwave Assisted Synthesis of N-(Ethoxycarbonylmethyl)-nucleobases: Building Blocks for PNAs
| العنوان: | Microwave Assisted Synthesis of N-(Ethoxycarbonylmethyl)-nucleobases: Building Blocks for PNAs |
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| المؤلفون: | Yong Li, Su-Hui Han, Guirong Qu |
| المصدر: | ChemInform. 36 |
| بيانات النشر: | Wiley, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Purine, chemistry.chemical_classification, Pyrimidine, 010405 organic chemistry, Chemistry, Synthon, Peptide, General Chemistry, General Medicine, Alkylation, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Nucleobase, chemistry.chemical_compound, Ethyl bromoacetate, Nucleic acid, Organic chemistry |
| الوصف: | The synthesis of N1/N9- (Ethoxycarbonylmethyl)pyrimidine/purine using as synthons for peptide nucleic acids has been described. Microwave irradiation provided the desired products by alkylation of the appropriately protected natural and substituted nucleobases with ethyl bromoacetate within 4–7 min in 48–85% yields. |
| تدمد: | 1522-2667 0931-7597 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2f526e2170aa3c0ac16c93efd47c3d https://doi.org/10.1002/chin.200538201 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8c2f526e2170aa3c0ac16c93efd47c3d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222667 09317597 |
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