Effect of triiodothyronine supplementation on thyrotropin-releasing hormone-induced growth hormone secretion in sex-linked dwarf and normal chicks
| العنوان: | Effect of triiodothyronine supplementation on thyrotropin-releasing hormone-induced growth hormone secretion in sex-linked dwarf and normal chicks |
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| المؤلفون: | Eddy Decuypere, L.M. Huybrechts, J.-L. Monvoisin, E.R. Kühn, Michèle Tixier-Boichard |
| المساهمون: | Génétique et Diversité Animales (GEDANIM), Institut National de la Recherche Agronomique (INRA)-AgroParisTech |
| المصدر: | General and Comparative Endocrinology General and Comparative Endocrinology, Elsevier, 1991, 84, pp.147-154 |
| بيانات النشر: | Elsevier BV, 1991. |
| سنة النشر: | 1991 |
| مصطلحات موضوعية: | Male, endocrine system, medicine.medical_specialty, endocrine system diseases, TRH, Microgram, Dwarfism, Thyrotropin-releasing hormone, 030209 endocrinology & metabolism, Stimulation, Biology, Weight Gain, SUPPLEMENTATION, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Endocrinology, Internal medicine, medicine, Animals, Dwarfism, Pituitary, Thyrotropin-Releasing Hormone, ComputingMilieux_MISCELLANEOUS, Analysis of Variance, Triiodothyronine, Dose-Response Relationship, Drug, 0402 animal and dairy science, 04 agricultural and veterinary sciences, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, medicine.disease, 040201 dairy & animal science, Growth hormone secretion, Dose–response relationship, Growth Hormone, Pituitary Gland, Female, Animal Science and Zoology, Chickens, Drug Antagonism, hormones, hormone substitutes, and hormone antagonists, Hormone |
| الوصف: | The effect of a dietary triiodothyronine (T3) supplement, of either 0.1 or 0.5 microgram/g of feed, was studied on the thyrotropin-releasing hormone (TRH)-induced growth hormone (GH) secretion in sex-linked dwarf (dw) or normal (Dw) chicks of both sexes. In normal chicks, 0.1 microgram/g T3 decreased plasma GH levels before TRH as well as the GH increase after TRH, and 0.5 microgram/g T3 totally suppressed any response to TRH, either at 4 or at 7 weeks of age. Dwarf chicks were more sensitive to TRH than normals when receiving either 0 or 0.1 microgram/g T3; 0.5 microgram/g T3 abolished the difference between genotypes at 4 weeks of age but not so clearly at 7 weeks of age, where dwarf females showed a slight but still significant GH increase after TRH. Interactions between genotype, TRH injection, and T3 treatments were often significant at 4 weeks of age and even more at 7 weeks of age. Dwarf chicks receiving 0.1 microgram/g T3, expected to have normal plasma T3 levels, showed a higher GH response after TRH. This suggests that other hormones may be involved in the regulation of this response, particularly IGF-I, which is known to remain at a low level in T3-treated dwarf chicks. |
| تدمد: | 0016-6480 1095-6840 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6c81536d31e87b37a3291c84d05094 https://doi.org/10.1016/0016-6480(91)90074-g |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....8c6c81536d31e87b37a3291c84d05094 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00166480 10956840 |
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